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Details on Person NOTCH1 stimulates HES1 transcription

Class:IdBlackBoxEvent:1980047
_displayNameNOTCH1 stimulates HES1 transcription
_doReleaseTRUE
_timestamp2017-01-31 16:55:45
authored[InstanceEdit:2121208] Egan, SE, Orlic-Milacic, M, 2011-11-14
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:1980046] Orlic-Milacic, M, 2011-11-08
edited[InstanceEdit:2106576] Orlic-Milacic, M, 2012-02-10
[InstanceEdit:2098673] D'Eustachio, P, 2012-02-06
[InstanceEdit:8959863] Orlic-Milacic, Marija, 2017-01-31
inferredFrom
input[EntityWithAccessionedSequence:2197548] HES1 gene [nucleoplasm] [Homo sapiens]
literatureReference[LiteratureReference:1602204] Signalling downstream of activated mammalian Notch
modified[InstanceEdit:2065272] Orlic-Milacic, M, 2012-01-20
[InstanceEdit:2065280] Orlic-Milacic, M, 2012-01-20
[InstanceEdit:2065286] Orlic-Milacic, M, 2012-01-20
[InstanceEdit:2122950] Orlic-Milacic, M, 2012-02-14
[InstanceEdit:4396368] Orlic-Milacic, M, 2013-08-22
[InstanceEdit:8959882] Orlic-Milacic, Marija, 2017-01-31
[InstanceEdit:8959887] Orlic-Milacic, Marija, 2017-01-31
[InstanceEdit:8959889] Orlic-Milacic, Marija, 2017-01-31
[InstanceEdit:9606200] Wu, G, 2018-04-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameNOTCH1 stimulates HES1 transcription
output[EntityWithAccessionedSequence:210825] HES1 [nucleoplasm] [Homo sapiens]
precedingEvent
regulatedBy[PositiveGeneExpressionRegulation:1980075] Positive gene expression regulation by 'NOTCH1 Coactivator Complex:HES1 Gene [nucleoplasm]'
releaseDate2012-03-13
reviewed[InstanceEdit:2121207] Haw, R, 2012-02-06
[InstanceEdit:8959885] Ito, Yoshiaki, 2017-01-31
[InstanceEdit:8959883] Chuang, Linda Shyue Huey, 2017-01-31
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:2158110] R-HSA-1980047.4
summation[Summation:2065285] NOTCH1 coactivator complex binds the promoter of HES1 gene a...
(hasEvent)[Pathway:210744] Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells [Homo sapiens]
[Pathway:2122947] NOTCH1 Intracellular Domain Regulates Transcription [Homo sapiens]
[Pathway:8941856] RUNX3 regulates NOTCH signaling [Homo sapiens]
[Pathway:9981845] NOTCH signaling regulates gene expression in endothelial stalk cells [Homo sapiens]
(normalReaction)[BlackBoxEvent:2220979] NOTCH1 PEST domain mutants stimulate HES1 transcription [Homo sapiens]
(precedingEvent)[Reaction:1912359] HES1 binds TLE [Homo sapiens]
(replacementInstances)[_Deleted:9606102] Deletion of instance: 210834
(updatedInstance)[_UpdateTracker:9787024] Update Tracker - [BlackBoxEvent:1980047] NOTCH1 stimulates HES1 transcription - v46:[addInput, add_removeRegulator, modifyText]
[_UpdateTracker:9788596] Update Tracker - [BlackBoxEvent:1980047] NOTCH1 stimulates HES1 transcription - v41:[modifyText]
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No pathways have been reviewed or authored by NOTCH1 stimulates HES1 transcription (1980047)
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