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Details on Person ERBB4 forms heterodimers with ERBB3

Class:Id	Reaction:1977958
_displayName	ERBB4 forms heterodimers with ERBB3
_doRelease	TRUE
_timestamp	2019-03-05 19:37:14
authored	[InstanceEdit:1972351] Orlic-Milacic, M, 2011-11-04 [InstanceEdit:9638819] Stern, David F, 2019-02-21
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:1977957] Orlic-Milacic, M, 2011-11-08
edited	[InstanceEdit:1972361] Matthews, L, 2011-11-07 [InstanceEdit:1972360] D'Eustachio, P, 2011-11-07 [InstanceEdit:9638824] Orlic-Milacic, Marija, 2019-03-05
input	[DefinedSet:1236393] NRGs/EGF-like ligands:ERBB4 [plasma membrane] [Homo sapiens] [Complex:1247495] NRG1/2:ERBB3 [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:1973954] The cellular response to neuregulins is governed by complex interactions of the erbB receptor family
modified	[InstanceEdit:1979912] Orlic-Milacic, M, 2011-11-08 [InstanceEdit:2008073] Orlic-Milacic, M, 2011-11-21 [InstanceEdit:9638822] Orlic-Milacic, Marija, 2019-03-05 [InstanceEdit:9638825] Orlic-Milacic, Marija, 2019-03-05 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ERBB4 forms heterodimers with ERBB3
output	[Complex:1977955] ERBB4:ERBB3 heterodimer [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:1236398] ERBB4 binds NRGs or EGF-like ligands [Homo sapiens] [Reaction:1247497] ERBB3 binds neuregulins [Homo sapiens]
releaseDate	2011-12-06
reviewed	[InstanceEdit:1979910] Harris, RC, 2011-11-11 [InstanceEdit:1979909] Zeng, F, 2011-11-11
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2016513] R-HSA-1977958.3
summation	[Summation:1977952] Ligand-stimulated ERBB4 was shown to form heterodimers with ...
(hasEvent)	[Pathway:1236394] Signaling by ERBB4 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9779614] Update Tracker - [Reaction:1977958] ERBB4 forms heterodimers with ERBB3 - v65:[modifyText]
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No pathways have been reviewed or authored by ERBB4 forms heterodimers with ERBB3 (1977958)