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Details on Person COASY phosphorylates DP-CoA

Class:IdReaction:196773
_displayNameCOASY phosphorylates DP-CoA
_doReleaseTRUE
_timestamp2023-07-26 14:30:18
authored[InstanceEdit:196747] Jassal, B, 2007-04-24 08:38:46
catalystActivity[CatalystActivity:196818] dephospho-CoA kinase activity of COASY [mitochondrial outer membrane]
compartment[Compartment:70101] cytosol
[Compartment:17906] mitochondrial outer membrane
created[InstanceEdit:196747] Jassal, B, 2007-04-24 08:38:46
input[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:196778] DP-CoA [cytosol]
literatureReference[LiteratureReference:196745] Identification and characterization of the gene encoding the human phosphopantetheine adenylyltransferase and dephospho-CoA kinase bifunctional enzyme (CoA synthase)
[LiteratureReference:196824] Subcellular localization and regulation of coenzyme A synthase
modified[InstanceEdit:197203] Jassal, B, 2007-05-02 09:36:52
[InstanceEdit:197283] Jassal, B, 2007-05-02 10:05:07
[InstanceEdit:199189] D'Eustachio, P, 2007-07-09 22:03:12
[InstanceEdit:200987] Gopinathrao, G, 2007-07-27 15:28:23
[InstanceEdit:732460] D'Eustachio, P, 2010-05-12
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:3165246] Jassal, B, 2013-02-22
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9837348] D'Eustachio, Peter, 2023-06-13
[InstanceEdit:9840789] D'Eustachio, Peter, 2023-07-26
nameCOASY phosphorylates DP-CoA
3'-dephospho-CoA + ATP => ADP + CoA + H(+)
Phosphorylation of dephospho-CoA to produce CoA
output[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:76194] CoA-SH [cytosol]
[SimpleEntity:70106] H+ [cytosol]
precedingEvent
previousReviewStatus[ReviewStatus:9821384] two stars
releaseDate2006-01-23
reviewed[InstanceEdit:9840788] Hill, David P, 2023-07-26
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:358796] R-HSA-196773.4
structureModified[InstanceEdit:9837348] D'Eustachio, Peter, 2023-06-13
summation[Summation:196792] The kinase activity of CoA synthase (COASY) catalyzes the ph...
(hasEvent)[Pathway:196783] Coenzyme A biosynthesis [Homo sapiens]
(precedingEvent)[Reaction:199202] Phosphopantetheine conjugation of the ACP domain of FAS [Homo sapiens]
[Reaction:199216] SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix [Homo sapiens]
[Reaction:9837333] SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP [Homo sapiens]
(updatedInstance)[_UpdateTracker:9787523] Update Tracker - [Reaction:196773] COASY phosphorylates DP-CoA - v44:[modifyText]
[_UpdateTracker:9842367] Update Tracker - [Reaction:196773] COASY phosphorylates DP-CoA - v86:[addOutput]
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