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Details on Person To transduce signals, the activated, GTP-bound Rho GTPases i...
| Class:Id | Summation:196505 |
|---|---|
| _displayName | To transduce signals, the activated, GTP-bound Rho GTPases i... |
| _timestamp | 2018-05-23 17:03:36 |
| created | [InstanceEdit:196504] Gopinathrao, G, 2007-04-23 11:38:48 |
| literatureReference | [LiteratureReference:195248] The role of the Rho GTPases in neuronal development |
| modified | [InstanceEdit:196630] Gopinathrao, G, 2007-04-23 20:29:15 [InstanceEdit:196706] Gopinathrao, G, 2007-04-23 21:00:56 [InstanceEdit:197003] D'Eustachio, P, 2007-04-28 21:22:45 [InstanceEdit:9609398] D'Eustachio, Peter, 2018-05-23 |
| text | To transduce signals, the activated, GTP-bound Rho GTPases interact with specific effector molecules. It has been observed that GEFs contribute to the signaling specificity of their downstream target GTPase via association with scaffolding molecules that link them and the GTPase to specific GTPase effectors (Govek et al., 2005). Some of the effector molecules implicated in actin and microtubule dynamics include diaphanous-related formins, Toca 1, WIP, WASP, Pak, p35/Cdk5, Wave, Nap125, MLCK, MLC, IRSp53. |
| (summation) | [Reaction:211435] Placeholder_Rho GTPase activates downstream effectors [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by To transduce signals, the activated, GTP-bound Rho GTPases i... (196505)
