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Details on Person 17-Hydroxypregnenolone and NAD+ react to form pregn-5-ene-3,...
| Class:Id | Summation:196369 |
|---|---|
| _displayName | 17-Hydroxypregnenolone and NAD+ react to form pregn-5-ene-3,... |
| _timestamp | 2007-04-20 21:30:53 |
| created | [InstanceEdit:196365] D'Eustachio, P, 2007-04-20 21:30:50 |
| text | 17-Hydroxypregnenolone and NAD+ react to form pregn-5-ene-3,20-dione-17-ol and NADH + H+. This reaction is catalyzed by the 3 beta-hydroxysteroid activity of 3-beta-hydroxysteroid dehydrogenase/isomerase (HSD3B) enzyme associated with the endoplasmic reticulum membrane. The active form of the enzyme is a homodimer. The enzyme occurs in two isoforms that are similar in their biochemical properties but differ in their tissue expression: type I (HSD3B1) is found in placenta and skin, while type II (HSD3B2) is found in the adrenal glands and gonads. |
| (summation) | [Reaction:196372] 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol [Homo sapiens] |
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No pathways have been reviewed or authored by 17-Hydroxypregnenolone and NAD+ react to form pregn-5-ene-3,... (196369)
