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Details on Person Cytochrome P450 11B2, mitochondrial (CYP11B2 aka aldosterone...

Class:IdSummation:196358
_displayNameCytochrome P450 11B2, mitochondrial (CYP11B2 aka aldosterone...
_timestamp2014-09-08 17:16:22
created[InstanceEdit:196338] D'Eustachio, P, 2007-04-20 18:44:40
modified[InstanceEdit:5600601] Jassal, Bijay, 2014-06-12
[InstanceEdit:5622022] Jassal, Bijay, 2014-09-08
textCytochrome P450 11B2, mitochondrial (CYP11B2 aka aldosterone hydroxylase) is an enzyme necessary for aldosterone biosynthesis via corticosterone (CORST) and 18-hydroxycorticosterone (18HCORST). The 11-beta oxidation of 11-deoxycorticosterone (11DCORST) leads to corticosterone (CORST) and 18-hydroxylation of this leads to 18-hydroxycorticosterone (18HCORST). 18-oxidation of 18HCORST yields aldosterone.
(summation)[Reaction:194017] CYP11B2 oxidises 11DCORST to CORST [Homo sapiens]
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