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Details on Person Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane]

Class:IdCandidateSet:1963572
_displayNamePhosphorylated ERBB2:ERBB3 heterodimers [plasma membrane]
_timestamp2012-08-13 11:30:19
compartment[Compartment:876] plasma membrane
created[InstanceEdit:1963565] Orlic-Milacic, M, 2011-11-03
hasCandidate
hasMember
modified[InstanceEdit:2448605] Orlic-Milacic, M, 2012-08-13
namePhosphorylated ERBB2:ERBB3 heterodimers
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:2017427] R-HSA-1963572.1
(hasComponent)[Complex:1248755] Shc1:Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] [Homo sapiens]
[Complex:1250191] NRG1/2:p-ERBB3:p-ERBB2:PIK3R1 [plasma membrane] [Homo sapiens]
[Complex:1306951] NRG1/2:p-10Y-ERBB3:p-ERBB2:GRB7 [plasma membrane] [Homo sapiens]
[Complex:1358729] NRG1/2:Ub-p-10Y-ERBB3:p-ERBB2 [plasma membrane] [Homo sapiens]
[Complex:1358734] NRG1/2:p-10Y-ERBB3:p-ERBB2:RNF41 [plasma membrane] [Homo sapiens]
(input)[Reaction:1248753] Shc1 binds phosphorylated ERBB2:ERBB3 heterodimers [Homo sapiens]
[Reaction:1250189] Binding of PI3K to ERBB2:p-ERBB3 heterodimer [Homo sapiens]
[Reaction:1306953] GRB7 binds phosphorylated heterodimer of ERBB2 and ERBB3 [Homo sapiens]
[Reaction:1358798] RNF41 binds neuregulin-activated ERBB3 [Homo sapiens]
(normalEntity)[EntityFunctionalStatus:9655363] gain_of_function of NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 L755S,(p-Y-ERBB2 L755M,p-Y-ERBB2 L755W) [plasma membrane]
[EntityFunctionalStatus:9655381] gain_of_function of Phosphorylated ERBB2 L755P:ERBB3 heterodimer [plasma membrane]
[EntityFunctionalStatus:9655414] gain_of_function of Phosphorylated ERBB2 T862A:ERBB3 heterodimer [plasma membrane]
[EntityFunctionalStatus:9655416] gain_of_function of Phosphorylated ERBB2 V777L,(ERBB2 V777M,ERBB2 V777E):ERBB3 heterodimer [plasma membrane]
[EntityFunctionalStatus:9655417] gain_of_function of Phosphorylated ERBB2 H878Y,(ERBB2 H878R):ERBB3 heterodimer [plasma membrane]
[EntityFunctionalStatus:9655418] gain_of_function of Phosphorylated ERBB2 T798I,ERBB2 T798M,(ERBB2 T733I):ERBB3 heterodimer [plasma membrane]
[EntityFunctionalStatus:9655419] gain_of_function of Phosphorylated ERBB2 L869R,(ERBB2 L869Q):ERBB3 heterodimer [plasma membrane]
[EntityFunctionalStatus:9655420] gain_of_function of Phosphorylated ERBB2 I767M:ERBB3 heterodimer [plasma membrane]
[EntityFunctionalStatus:9664669] gain_of_function of p-ERBB2 KD mutants:NRG1/NRG2:p-10Y-ERBB3 [plasma membrane]
(updatedInstance)[_UpdateTracker:9872478] Update Tracker - [CandidateSet:1963572] Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] - v41:[updateContainedMemberOrCandidate]
[_UpdateTracker:9873093] Update Tracker - [CandidateSet:1963572] Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] - v42:[removeCompartment]
[_UpdateTracker:9900704] Update Tracker - [CandidateSet:1963572] Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] - v70:[updateContainedMemberOrCandidate]
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No pathways have been reviewed or authored by Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (1963572)
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