Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person Pregnenolone and NAD+ react to form pregn-5-ene-3,20-dione a...
| Class:Id | Summation:196331 |
|---|---|
| _displayName | Pregnenolone and NAD+ react to form pregn-5-ene-3,20-dione a... |
| _timestamp | 2007-04-20 18:44:57 |
| created | [InstanceEdit:196338] D'Eustachio, P, 2007-04-20 18:44:40 |
| text | Pregnenolone and NAD+ react to form pregn-5-ene-3,20-dione and NADH + H+. This reaction is catalyzed by the 3 beta-hydroxysteroid activity of 3-beta-hydroxysteroid dehydrogenase/isomerase (HSD3B) enzyme associated with the endoplasmic reticulum membrane. The active form of the enzyme is a homodimer. The enzyme occurs in two isoforms that are similar in their biochemical properties but differ in their tissue expression: type I (HSD3B1) is found in placenta and skin, while type II (HSD3B2) is found in the adrenal glands and gonads. |
| (summation) | [Reaction:196350] Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by Pregnenolone and NAD+ react to form pregn-5-ene-3,20-dione a... (196331)
