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Details on Person Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation

Class:IdLiteratureReference:196265
_displayNameMechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation
_timestamp2007-04-19 13:44:32
author[Person:196283] Ha, Nam-Chul
[Person:196277] Tonozuka, Takashi
[Person:196271] Stamos, Jennifer
[Person:196278] Choi, Hee-Jung
[Person:196275] Weis, William I
created[InstanceEdit:196263] Matthews, L, 2007-04-19 13:43:50
journalMol Cell
pages511-21
pubMedIdentifier15327768
titleMechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation
volume15
year2004
(literatureReference)[Reaction:209060] Human APC is further phosphorylated by Murine GSK3beta [Homo sapiens]
[Reaction:209065] Human APC is further phosphorylated by Murine CKIepsilon [Homo sapiens]
[Reaction:209132] Human APC is initially phosphorylated by Murine CKIepsilon [Homo sapiens]
[Reaction:209144] Human APC is finally phosphorylated by Murine GSK3beta [Homo sapiens]
[Pathway:4839744] Signaling by APC mutants [Homo sapiens]
[Summation:195291] Beta-catenin associates with the destruction complex through...
[Summation:195307] The phosphorylation of the 20 aa repeats in APC results in a...
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