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Details on Person PP2A [cytosol]

Class:IdComplex:196206
_displayNamePP2A [cytosol]
_timestamp2008-06-20 12:43:23
compartment[Compartment:70101] cytosol
created[InstanceEdit:196217] Matthews, L, 2007-04-18 13:41:15
hasComponent
modified[InstanceEdit:196230] Matthews, L, 2007-04-19 08:03:24
namePP2A
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:362558] R-HSA-196206.1
(activeUnit)[CatalystActivity:3601580] protein serine/threonine phosphatase activity of p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol]
(hasComponent)[Complex:195250] AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] [Homo sapiens]
[Complex:195297] p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] [Homo sapiens]
[Complex:195322] p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] [Homo sapiens]
[Complex:196222] p-AXIN:CK1alpha:GSK3B:phospho-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] [Homo sapiens]
[Complex:375305] Kinetochore [cytosol] [Homo sapiens]
[Complex:389533] CTLA4 dimer:PP2A [plasma membrane] [Homo sapiens]
[Complex:389747] CD28:PP2A [plasma membrane] [Homo sapiens]
[Complex:432144] p-PECAM:PP2A [plasma membrane] [Homo sapiens]
[Complex:3601577] p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] [Homo sapiens]
[Complex:5339714] p-AXIN:GSK3 del304-316:CK1alpha:APC:PP2A:AMER1 complex [cytosol] [Homo sapiens]
List all 12 refering instances
(input)[Reaction:195251] Assembly of the destruction complex [Homo sapiens]
[Reaction:389532] PP2A binds CTLA4 dimer [Homo sapiens]
[Reaction:389757] PP2A binds CD28 [Homo sapiens]
[Reaction:432143] PECAM-1 binds PP2A [Homo sapiens]
[FailedReaction:4791278] APC truncation mutants have impaired AXIN binding [Homo sapiens]
[FailedReaction:4839734] AXIN mutants destabilize the destruction complex [Homo sapiens]
[FailedReaction:4839746] Truncated AMER1 mutants destabilize the destruction complex [Homo sapiens]
[Reaction:8857925] Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 [Homo sapiens]
[Reaction:9735131] OSBP binds CHOL, PTPN7 and PP2A [Homo sapiens]
(output)[Reaction:201685] Beta-catenin is released from the destruction complex [Homo sapiens]
[Reaction:388833] Phosphorylation of CTLA-4 [Homo sapiens]
(physicalEntity)[CatalystActivity:390328] phosphatidate phosphatase activity of PP2A [cytosol]
[CatalystActivity:5672955] protein serine/threonine phosphatase activity of PP2A [cytosol]
(updatedInstance)[_UpdateTracker:9871286] Update Tracker - [Complex:196206] PP2A [cytosol] - v39:[updateContainedComponent]
[_UpdateTracker:9873599] Update Tracker - [Complex:196206] PP2A [cytosol] - v43:[updateContainedComponent]
[_UpdateTracker:9878952] Update Tracker - [Complex:196206] PP2A [cytosol] - v44:[updateContainedComponent]
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No pathways have been reviewed or authored by PP2A [cytosol] (196206)
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