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Details on Person Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol

Class:IdReaction:195690
_displayNameZymosterol is isomerized to cholesta-7,24-dien-3beta-ol
_doReleaseTRUE
_timestamp2025-04-11 19:40:15
authored[InstanceEdit:196418] D'Eustachio, P, 2007-04-21 18:31:40
catalystActivity[CatalystActivity:195674] steroid Delta-isomerase activity of EBP [endoplasmic reticulum membrane]
catalystActivityReference[CatalystActivityReference:9643176] steroid delta-isomerase activity of EBP [endoplasmic reticulum membrane] Mutations in a delta 8-delta 7 sterol isomerase in the tattered mouse and X-linked dominant chondrodysplasia punctata. jderry@immunex.com.
compartment[Compartment:12045] endoplasmic reticulum membrane
created[InstanceEdit:195668] D'Eustachio, P, 2007-04-12 15:55:15
crossReference[DatabaseIdentifier:9945223] RHEA:34000
edited[InstanceEdit:196418] D'Eustachio, P, 2007-04-21 18:31:40
input[SimpleEntity:194691] ZYMOL [endoplasmic reticulum membrane]
literatureReference[LiteratureReference:195673] Mutations in a delta 8-delta 7 sterol isomerase in the tattered mouse and X-linked dominant chondrodysplasia punctata. jderry@immunex.com.
[LiteratureReference:195694] Mutations in the gene encoding 3 beta-hydroxysteroid-delta 8, delta 7-isomerase cause X-linked dominant Conradi-Hunermann syndrome
modified[InstanceEdit:196422] D'Eustachio, P, 2007-04-21 18:35:08
[InstanceEdit:197014] Gopinathrao, G, 2007-04-30 12:01:02
[InstanceEdit:9643047] Wu, G, 2019-04-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9945226] D'Eustachio, Peter, 2025-04-11
nameZymosterol is isomerized to cholesta-7,24-dien-3beta-ol
zymosterol => 5alpha-cholesta-7,24-dien-3beta-ol
output[SimpleEntity:195691] CHdOL [endoplasmic reticulum membrane]
precedingEvent
releaseDate2007-02-20
reviewed[InstanceEdit:196409] Jassal, B, 2007-04-21 18:33:24
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:360934] R-HSA-195690.4
summation[Summation:195656] Isomerization of zymosterol to cholesta-7,24-dien-3beta-ol i...
(hasEvent)[Pathway:6807047] Cholesterol biosynthesis via desmosterol (Bloch pathway) [Homo sapiens]
[Pathway:8962003] Orphan 7 events
(precedingEvent)[Reaction:195664] Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol [Homo sapiens]
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