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Details on Person Isomerization of zymosterol to cholesta-7,24-dien-3beta-ol i...

Class:IdSummation:195656
_displayNameIsomerization of zymosterol to cholesta-7,24-dien-3beta-ol i...
_timestamp2007-04-12 15:55:27
created[InstanceEdit:195668] D'Eustachio, P, 2007-04-12 15:55:15
literatureReference[LiteratureReference:195663] Microsomal enzymes of cholesterol biosynthesis from lanosterol. Solubilization and purification of steroid 8-isomerase.
textIsomerization of zymosterol to cholesta-7,24-dien-3beta-ol is catalyzed by EBP in the endoplasmic reticulum. The biochemical details of the reaction have been established through studies of purified rat EBP; the role of the human enzyme has been established through studies of patients deficient in it (Derry et al. 1999; Braverman et al. 1999).
(summation)[Reaction:195690] Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol [Homo sapiens]
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