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Details on Person A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells
| Class:Id | LiteratureReference:195484 |
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| _displayName | A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells |
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| _timestamp | 2007-04-08 23:53:04 |
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| author | [Person:195476] Takahashi, T
[Person:195463] Yamaguchi, S
[Person:195480] Chida, K
[Person:179876] Shibuya, M |
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| created | [InstanceEdit:195494] Gopinathrao, G, 2007-04-08 23:52:30 |
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| journal | EMBO J |
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| pages | 2768-78 |
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| pubMedIdentifier | 11387210 |
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| title | A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells |
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| volume | 20 |
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| year | 2001 |
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| (literatureReference) | [Summation:4420175] Following tyrosine phosphorylation and activation, PLCG1 dis...
[Reaction:194310] VEGF-A,C,D bind to VEGFR2 leading to receptor dimerization [Homo sapiens]
[Reaction:194311] VEGFA,B,PLGF bind to VEGFR1 leading to receptor dimerization [Homo sapiens]
[Reaction:4420153] p-6Y-VEGFR2 binds PLCG1 [Homo sapiens]
[Reaction:4420202] PLCG1 disassociates from VEGFR2 and translocate to PM [Homo sapiens] |
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