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Details on Person CSNK1A1 [cytosol]
Class:Id EntityWithAccessionedSequence:195263
_displayName CSNK1A1 [cytosol]
_timestamp 2013-06-24 21:15:44
compartment [Compartment:70101] cytosol
created [InstanceEdit:195266] Matthews, L, 2007-04-03 12:37:29
endCoordinate 337
modified [InstanceEdit:3132750] Wu, G, 2013-02-13 [InstanceEdit:3601592] Rothfels, K, 2013-05-22 [InstanceEdit:3632907] Wu, G, 2013-05-28 [InstanceEdit:3772380] Rothfels, K, 2013-06-24
name CSNK1A1 CK1alpha CSNK1A1
referenceEntity [ReferenceGeneProduct:57867] UniProt:P48729 CSNK1A1 [Homo sapiens]
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:370538] R-HSA-195263.1
startCoordinate 2
(hasComponent) [Complex:195250] AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] [Homo sapiens] [Complex:195297] p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] [Homo sapiens] [Complex:195322] p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] [Homo sapiens] [Complex:196222] p-AXIN:CK1alpha:GSK3B:phospho-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] [Homo sapiens] [Complex:206859] Phospho (4 sites) beta-catenin:Phospho (3 sites) Axin1:Phospho (6 sites) APC:PP2A:CKIalpha:CKIepsilon:GSK3beta [cytosol] [Homo sapiens] [Complex:206870] Phospho (3 sites) Axin1:Phospho (6 sites) APC:PP2A:CKIalpha:CKIepsilon:GSK3beta [cytosol] [Homo sapiens] [Complex:3601577] p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] [Homo sapiens] [Complex:5339714] p-AXIN:GSK3 del304-316:CK1alpha:APC:PP2A:AMER1 complex [cytosol] [Homo sapiens] [Complex:9666609] phosphorylated ubiquitination mutants of CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] [Homo sapiens]
(hasMember) [CandidateSet:195284] CK1alpha (GSK3) [cytosol] [Homo sapiens]
(input) [Reaction:195251] Assembly of the destruction complex [Homo sapiens] [FailedReaction:4791278] APC truncation mutants have impaired AXIN binding [Homo sapiens] [FailedReaction:4839734] AXIN mutants destabilize the destruction complex [Homo sapiens] [FailedReaction:4839746] Truncated AMER1 mutants destabilize the destruction complex [Homo sapiens]
(output) [Reaction:201685] Beta-catenin is released from the destruction complex [Homo sapiens]
(physicalEntity) [CatalystActivity:5610635] protein serine/threonine kinase activity of CSNK1A1 [cytosol]
(updatedInstance) [_UpdateTracker:9877044] Update Tracker - [EntityWithAccessionedSequence:195263] CSNK1A1 [cytosol] - v44:[modifyEndCoordinate] [_UpdateTracker:9880978] Update Tracker - [EntityWithAccessionedSequence:195263] CSNK1A1 [cytosol] - v45:[addName] [_UpdateTracker:9888352] Update Tracker - [EntityWithAccessionedSequence:195263] CSNK1A1 [cytosol] - v46:[modifyStartCoordinate, removeName]
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Pathways
No pathways have been reviewed or authored by CSNK1A1 [cytosol] (195263)