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Details on Person UniProt:P98171 ARHGAP4
| Class:Id | ReferenceGeneProduct:195094 |
|---|---|
| _chainChangeLog | chain:1-946 added on Fri February 6 2015 |
| _displayName | UniProt:P98171 ARHGAP4 |
| _timestamp | 2024-11-03 20:02:51 |
| chain | chain:1-946 |
| checksum | ED3D48C5DAA24969 |
| comment | FUNCTION Inhibitory effect on stress fiber organization. May down-regulate Rho-like GTPase in hematopoietic cells.SUBUNIT Interacts with NCKAP1L.INTERACTION Just below the plasma membrane.ALTERNATIVE PRODUCTS Predominantly in hematopoietic cells (spleen, thymus and leukocytes); low levels in placenta, lung and various fetal tissues. |
| created | [InstanceEdit:195085] Gopinathrao, G, 2007-04-02 18:48:36 |
| description | recommendedName: fullName evidence="8"Rho GTPase-activating protein 4 alternativeName: Rho-GAP hematopoietic protein C1 alternativeName: Rho-type GTPase-activating protein 4 alternativeName: p115 |
| geneName | ARHGAP4 KIAA0131 RGC1 RHOGAP4 |
| identifier | P98171 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Alternative splicing Coiled coil Cytoplasm GTPase activation Phosphoprotein Proteomics identification Reference proteome SH3 domain |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | ARHGAP4 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:9003193] ENSEMBL:ENSG00000089820 ARHGAP4 [Homo sapiens] |
| secondaryIdentifier | RHG04_HUMAN Q14144 Q86UY3 |
| sequenceLength | 946 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:8974453] UniProt:P98171-1 ARHGAP4 [Homo sapiens] [ReferenceIsoform:8974454] UniProt:P98171-2 ARHGAP4 [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:195112] ARHGAP4 [cytosol] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P98171 ARHGAP4 (195094)
