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Details on Person UniProt:Q99819 ARHGDIG
| Class:Id | ReferenceGeneProduct:195092 |
|---|---|
| _chainChangeLog | chain:1-225 added on Sat February 7 2015 |
| _displayName | UniProt:Q99819 ARHGDIG |
| _timestamp | 2024-11-03 19:45:55 |
| chain | chain:1-225 |
| checksum | AFC4576E6BE0E9BD |
| comment | FUNCTION Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.INTERACTION Primarily expressed in pancreas and brain.SIMILARITY Belongs to the Rho GDI family. |
| created | [InstanceEdit:195085] Gopinathrao, G, 2007-04-02 18:48:36 |
| description | recommendedName: Rho GDP-dissociation inhibitor 3 shortName: Rho GDI 3 alternativeName: Rho-GDI gamma |
| geneName | ARHGDIG |
| identifier | Q99819 |
| isSequenceChanged | FALSE |
| keyword | Cytoplasm GTPase activation Proteomics identification Reference proteome |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | ARHGDIG |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:9002360] ENSEMBL:ENSG00000242173 ARHGDIG [Homo sapiens] |
| secondaryIdentifier | GDIR3_HUMAN Q4TT69 Q96S29 |
| sequenceLength | 225 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:195087] ARHGDIG [cytosol] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q99819 ARHGDIG (195092)
