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Details on Person Sterol dependent regulation of human TM7SF2 gene expression: role of the encoded 3beta-hydroxysterol Delta14-reductase in human cholesterol biosynthesis
| Class:Id | LiteratureReference:194703 |
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| _displayName | Sterol dependent regulation of human TM7SF2 gene expression: role of the encoded 3beta-hydroxysterol Delta14-reductase in human cholesterol biosynthesis |
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| _timestamp | 2007-03-22 15:07:44 |
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| author | [Person:194713] Bennati, AM
[Person:194729] Castelli, M
[Person:194630] Della Fazia, MA
[Person:194727] Beccari, T
[Person:194645] Caruso, D
[Person:194663] Servillo, G
[Person:194665] Roberti, R |
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| created | [InstanceEdit:194683] D'Eustachio, P, 2007-03-22 16:07:19 |
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| journal | Biochim Biophys Acta |
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| pages | 677-85 |
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| pubMedIdentifier | 16784888 |
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| title | Sterol dependent regulation of human TM7SF2 gene expression: role of the encoded 3beta-hydroxysterol Delta14-reductase in human cholesterol biosynthesis |
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| volume | 1761 |
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| year | 2006 |
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| (literatureReference) | [Summation:194662] 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol and NADPH + H...
[Reaction:194698] 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] [Homo sapiens]
[Reaction:9946140] TM7SF2 reduces 4,4-diMeCholesta-8,14-dien-3-ol to 4,4-diMe5-cholest-8-en-3-ol [Homo sapiens]
[RegulationReference:9642328] Positive gene expression regulation by 'SREBP1A,1C,2:NF-Y:TM7SF2 gene [nucleoplasm]' Activation of TM7SF2 promoter by SREBP-2 depends on a new sterol regulatory element, a GC-box, and an inverted CCAAT-box
[CatalystActivityReference:9946138] Delta14-sterol reductase activity of TM7SF2 [endoplasmic reticulum membrane] Sterol dependent regulation of human TM7SF2 gene expression: role of the encoded 3beta-hydroxysterol Delta14-reductase in human cholesterol biosynthesis |
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