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Details on Person SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol

Class:IdReaction:194187
_displayNameSLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol
_doReleaseTRUE
_timestamp2021-06-14 13:46:12
authored[InstanceEdit:194157] D'Eustachio, P, 2007-03-09 21:29:31
catalystActivity[CatalystActivity:194178] bile acid:sodium symporter activity of SLC10A2 [plasma membrane]
compartment[Compartment:876] plasma membrane
created[InstanceEdit:194163] D'Eustachio, P, 2007-03-09 21:33:16
edited[InstanceEdit:194157] D'Eustachio, P, 2007-03-09 21:29:31
input[SimpleEntity:74113] Na+ [extracellular region]
[DefinedSet:192483] bile salts and acids [extracellular region]
literatureReference[LiteratureReference:194094] Bile salt transporters: molecular characterization, function, and regulation
[LiteratureReference:193474] Enterohepatic bile salt transporters in normal physiology and liver disease
[LiteratureReference:5625194] Insights into the bile acid transportation system: the human ileal lipid-binding protein-cholyltaurine complex and its comparison with homologous structures
modified[InstanceEdit:195718] Gopinathrao, G, 2007-04-16 17:35:22
[InstanceEdit:197014] Gopinathrao, G, 2007-04-30 12:01:02
[InstanceEdit:197116] D'Eustachio, P, 2007-04-30 14:50:16
[InstanceEdit:5340205] Jassal, Bijay, 2014-03-12
[InstanceEdit:5358731] Jassal, Bijay, 2014-04-03
[InstanceEdit:5625190] Jassal, Bijay, 2014-10-03
[InstanceEdit:5625193] Jassal, Bijay, 2014-10-03
[InstanceEdit:5674209] Jassal, Bijay, 2015-02-11
[InstanceEdit:9606200] Wu, G, 2018-04-19
[InstanceEdit:9733974] Jassal, Bijay, 2021-06-14
[InstanceEdit:9733997] Jassal, Bijay, 2021-06-14
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameSLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol
Co-transport (influx) of bile salts and acids and sodium ions by ASBT
output[DefinedSet:194156] bile salts and acids [cytosol]
[SimpleEntity:83910] Na+ [cytosol]
precedingEvent
regulatedBy[PositiveRegulation:5340412] Positive regulation by 'NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm]'
releaseDate2007-05-15
reviewed[InstanceEdit:197117] D'Eustachio, P, 2007-04-30 14:43:26
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:5625191] Swaan, Peter, 2014-10-03
[InstanceEdit:5674206] Jassal, Bijay, 2015-02-11
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:360243] R-HSA-194187.4
summation[Summation:194174] A molecule of extracellular bile salt or bile acid (cholate,...
(hasEvent)[Pathway:159418] Recycling of bile acids and salts [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9733973] Bile salts bind FABP6 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9776069] Update Tracker - [Reaction:194187] SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol - v78:[add_removeOutput, modifyText, removeInput]
[_UpdateTracker:9785769] Update Tracker - [Reaction:194187] SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol - v51:[add_removeLiteratureReference, modifyText]
[_UpdateTracker:9786518] Update Tracker - [Reaction:194187] SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol - v49:[addLiteratureReference, addRegulator, modifyText]
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