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Details on Person Transport (influx) of bile salts and acids by OATP-A

Class:Id	Reaction:194130
_displayName	Transport (influx) of bile salts and acids by OATP-A
_doRelease	TRUE
_timestamp	2025-06-10 14:39:14
authored	[InstanceEdit:194157] D'Eustachio, P, 2007-03-09 21:29:31
catalystActivity	[CatalystActivity:194128] bile acid transmembrane transporter activity of SLCO1A2 [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:194078] D'Eustachio, P, 2007-03-08 15:03:08
crossReference	[DatabaseIdentifier:9955300] RHEA:71704 [DatabaseIdentifier:9955296] RHEA:71852 [DatabaseIdentifier:9955308] RHEA:71856 [DatabaseIdentifier:9955299] RHEA:71860 [DatabaseIdentifier:9955310] RHEA:72684 [DatabaseIdentifier:9955309] RHEA:75052
edited	[InstanceEdit:194157] D'Eustachio, P, 2007-03-09 21:29:31
input	[DefinedSet:192483] bile salts and acids [extracellular region]
literatureReference	[LiteratureReference:194109] Molecular and functional characterization of an organic anion transporting polypeptide cloned from human liver
modified	[InstanceEdit:194163] D'Eustachio, P, 2007-03-09 21:33:16 [InstanceEdit:195718] Gopinathrao, G, 2007-04-16 17:35:22 [InstanceEdit:197014] Gopinathrao, G, 2007-04-30 12:01:02 [InstanceEdit:197116] D'Eustachio, P, 2007-04-30 14:50:16 [InstanceEdit:9733974] Jassal, Bijay, 2021-06-14 [InstanceEdit:9758052] Jassal, Bijay, 2021-11-09 [InstanceEdit:9758053] Jassal, Bijay, 2021-11-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9955297] Stephan, Ralf, 2025-06-10
name	Transport (influx) of bile salts and acids by OATP-A SLCO1A2 transports
output	[DefinedSet:194156] bile salts and acids [cytosol]
precedingEvent	[Reaction:194153] ABCC3 transports bile salts from cytosol to extracellular region [Homo sapiens] [BlackBoxEvent:9733969] Bile salts dissociate from FABP6 [Homo sapiens]
releaseDate	2007-05-15
reviewed	[InstanceEdit:197117] D'Eustachio, P, 2007-04-30 14:43:26
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:358711] R-HSA-194130.5
summation	[Summation:194087] A molecule of extracellular bile salt (glyco- or taurocholat...
(hasEvent)	[Pathway:159418] Recycling of bile acids and salts [Homo sapiens] [Pathway:879518] Organic anion transport by SLCO transporters [Homo sapiens] [Pathway:5619059] Defective ALB causes Dysalbuminemic hyperthyroxinemia (DH) [Homo sapiens]
(precedingEvent)	[Reaction:159425] Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) [Homo sapiens] [Reaction:193362] ABCB11 transports bile salts from cytosol to extracellular region [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9775393] Update Tracker - [Reaction:194130] Transport (influx) of bile salts and acids by OATP-A - v79:[add_removeOutput] [_UpdateTracker:9775734] Update Tracker - [Reaction:194130] Transport (influx) of bile salts and acids by OATP-A - v78:[add_removeInput, removeOutput]
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