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Details on Person SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol

Class:Id	Reaction:194079
_displayName	SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol
_doRelease	TRUE
_timestamp	2025-06-10 14:38:08
authored	[InstanceEdit:194157] D'Eustachio, P, 2007-03-09 21:29:31
catalystActivity	[CatalystActivity:194088] bile acid transmembrane transporter activity of SLCO1B3 [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:194078] D'Eustachio, P, 2007-03-08 15:03:08
crossReference	[DatabaseIdentifier:9955300] RHEA:71704 [DatabaseIdentifier:9955296] RHEA:71852
edited	[InstanceEdit:194157] D'Eustachio, P, 2007-03-09 21:29:31
input	[DefinedSet:194117] GCCA, TCCA [extracellular region]
literatureReference	[LiteratureReference:194124] Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver
modified	[InstanceEdit:194163] D'Eustachio, P, 2007-03-09 21:33:16 [InstanceEdit:195718] Gopinathrao, G, 2007-04-16 17:35:22 [InstanceEdit:197014] Gopinathrao, G, 2007-04-30 12:01:02 [InstanceEdit:197116] D'Eustachio, P, 2007-04-30 14:50:16 [InstanceEdit:5661189] Jassal, Bijay, 2015-01-09 [InstanceEdit:9733974] Jassal, Bijay, 2021-06-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9955297] Stephan, Ralf, 2025-06-10
name	SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol
output	[DefinedSet:194097] GCCA, TCCA [cytosol]
precedingEvent	[Reaction:194153] ABCC3 transports bile salts from cytosol to extracellular region [Homo sapiens] [BlackBoxEvent:9733969] Bile salts dissociate from FABP6 [Homo sapiens]
releaseDate	2007-05-15
reviewed	[InstanceEdit:197117] D'Eustachio, P, 2007-04-30 14:43:26
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:359414] R-HSA-194079.4
summation	[Summation:194106] A molecule of extracellular glycocholate or taurocholate is ...
(hasEvent)	[Pathway:159418] Recycling of bile acids and salts [Homo sapiens] [Pathway:879518] Organic anion transport by SLCO transporters [Homo sapiens] [Pathway:5619059] Defective ALB causes Dysalbuminemic hyperthyroxinemia (DH) [Homo sapiens]
(precedingEvent)	[Reaction:193362] ABCB11 transports bile salts from cytosol to extracellular region [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9775646] Update Tracker - [Reaction:194079] SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol - v78:[add_removeInput, removeOutput]
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