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Details on Person 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol

Class:IdReaction:193841
_displayName5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol
_doReleaseTRUE
_timestamp2011-02-24 14:06:01
authored[InstanceEdit:193805] D'Eustachio, P, 2007-02-27 21:49:11
catalystActivity[CatalystActivity:192098] alcohol dehydrogenase (NADP+) activity of Aldo-keto reductase family [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:193803] D'Eustachio, P, 2007-02-27 22:01:10
edited[InstanceEdit:193805] D'Eustachio, P, 2007-02-27 21:49:11
input[SimpleEntity:193830] 5beta-cholestan-7alpha,27-diol-3-one [cytosol]
[SimpleEntity:29364] NADPH [cytosol]
[SimpleEntity:70106] H+ [cytosol]
literatureReference[LiteratureReference:192140] Human types 1 and 3 3 alpha-hydroxysteroid dehydrogenases: differential lability and tissue distribution
modified[InstanceEdit:195718] Gopinathrao, G, 2007-04-16 17:35:22
[InstanceEdit:197014] Gopinathrao, G, 2007-04-30 12:01:02
[InstanceEdit:197116] D'Eustachio, P, 2007-04-30 14:50:16
[InstanceEdit:1221554] Jassal, B, 2011-02-24
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol
5beta-cholestan-7alpha,27-diol-3-one+ NADPH + H+ => 5beta-cholestan-3alpha,7alpha,27-triol + NADP+
output[SimpleEntity:193842] 5beta-cholestan-3alpha,7alpha,26-triol [cytosol]
[SimpleEntity:29366] NADP+ [cytosol]
precedingEvent
releaseDate2007-05-15
reviewed[InstanceEdit:197117] D'Eustachio, P, 2007-04-30 14:43:26
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359221] R-HSA-193841.2
summation[Summation:193811] 5Beta-cholesten-7alpha,27-diol-3-one and NADPH + H+ form 5be...
(hasEvent)[Pathway:193807] Synthesis of bile acids and bile salts via 27-hydroxycholesterol [Homo sapiens]
(precedingEvent)[Reaction:193808] 5beta-cholestan-3alpha,7alpha,27-triol is translocated from the cytosol to the mitochondrial matrix [Homo sapiens]
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