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Details on Person 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is translocated from the cytosol to the mitochondrial matrix

Class:Id	Reaction:193832
_displayName	5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is translocated from the cytosol to the mitochondrial matrix
_doRelease	TRUE
_timestamp	2025-08-12 22:17:53
authored	[InstanceEdit:193805] D'Eustachio, P, 2007-02-27 21:49:11
catalystActivity	[CatalystActivity:9948409] alcohol transmembrane transporter activity of unknown START protein [mitochondrial inner membrane]
catalystActivityReference	[CatalystActivityReference:9948410] alcohol transmembrane transporter activity of unknown START protein [mitochondrial inner membrane] The enzymes, regulation, and genetics of bile acid synthesis
compartment	[Compartment:70616] mitochondrial inner membrane
created	[InstanceEdit:193803] D'Eustachio, P, 2007-02-27 22:01:10
edited	[InstanceEdit:193805] D'Eustachio, P, 2007-02-27 21:49:11
input	[SimpleEntity:193843] 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol [cytosol]
internalReviewed	[InstanceEdit:9948437] D'Eustachio, Peter, 2025-05-20
literatureReference	[LiteratureReference:192080] The enzymes, regulation, and genetics of bile acid synthesis
modified	[InstanceEdit:195718] Gopinathrao, G, 2007-04-16 17:35:22 [InstanceEdit:197014] Gopinathrao, G, 2007-04-30 12:01:02 [InstanceEdit:197116] D'Eustachio, P, 2007-04-30 14:50:16 [InstanceEdit:198215] D'Eustachio, P, 2007-05-26 19:03:08 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9948408] D'Eustachio, Peter, 2025-05-20 [InstanceEdit:9948436] D'Eustachio, Peter, 2025-05-20 [InstanceEdit:9962971] D'Eustachio, Peter, 2025-08-12
name	5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is translocated from the cytosol to the mitochondrial matrix
output	[SimpleEntity:192201] 5bCHOL3a,7a,12a,27-tetrol [mitochondrial matrix]
precedingEvent	[Reaction:193800] 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol [Homo sapiens] [Reaction:193821] 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one [Homo sapiens]
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2007-05-15
reviewed	[InstanceEdit:197117] D'Eustachio, P, 2007-04-30 14:43:26 [InstanceEdit:9962972] Hill, David P, 2025-08-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360519] R-HSA-193832.4
structureModified	[InstanceEdit:9948408] D'Eustachio, Peter, 2025-05-20
summation	[Summation:193834] 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is transloca...
(hasEvent)	[Pathway:193807] Synthesis of bile acids and bile salts via 27-hydroxycholesterol [Homo sapiens]
(precedingEvent)	[Reaction:192042] 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9792332] Update Tracker - [Reaction:193832] 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is translocated from the cytosol to the mitochondrial matrix - v22:[addLiteratureReference] [_UpdateTracker:9953652] Update Tracker - [Reaction:193832] 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is translocated from the cytosol to the mitochondrial matrix - v93:[removeCatalystActivity]
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No pathways have been reviewed or authored by 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is translocated from the cytosol to the mitochondrial matrix (193832)