Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person 3,7,24THCA-CoA is translocated from the cytosol to the peroxisome

Class:Id	Reaction:193753
_displayName	3,7,24THCA-CoA is translocated from the cytosol to the peroxisome
_doRelease	TRUE
_timestamp	2026-04-23 19:20:54
authored	[InstanceEdit:193783] D'Eustachio, P, 2007-02-23 20:35:09
catalystActivity	[CatalystActivity:9987431] ATPase-coupled transmembrane transporter activity of ABCD3 dimer [peroxisomal membrane]
catalystActivityReference	[CatalystActivityReference:9987430] ATPase-coupled transmembrane transporter activity of ABCD3 dimer [peroxisomal membrane] A novel bile acid biosynthesis defect due to a deficiency of peroxisomal ABCD3
compartment	[Compartment:70101] cytosol [Compartment:17951] peroxisomal matrix
created	[InstanceEdit:193768] D'Eustachio, P, 2007-02-23 20:48:08
edited	[InstanceEdit:193783] D'Eustachio, P, 2007-02-23 20:35:09
goBiologicalProcess	[GO_BiologicalProcess:25870] peroxisomal membrane transport
input	[SimpleEntity:193739] 3,7,24THCA-CoA [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:29356] H2O [cytosol]
internalReviewed	[InstanceEdit:9987449] D'Eustachio, Peter, 2026-04-15
literatureReference	[LiteratureReference:9987436] A novel bile acid biosynthesis defect due to a deficiency of peroxisomal ABCD3 [LiteratureReference:9987441] Live cell FRET microscopy: homo- and heterodimerization of two human peroxisomal ABC transporters, the adrenoleukodystrophy protein (ALDP, ABCD1) and PMP70 (ABCD3) [LiteratureReference:192080] The enzymes, regulation, and genetics of bile acid synthesis [LiteratureReference:193419] ATP-dependent transport of bile acid intermediates across rat liver peroxisomal membranes
modified	[InstanceEdit:195718] Gopinathrao, G, 2007-04-16 17:35:22 [InstanceEdit:197014] Gopinathrao, G, 2007-04-30 12:01:02 [InstanceEdit:197116] D'Eustachio, P, 2007-04-30 14:50:16 [InstanceEdit:198215] D'Eustachio, P, 2007-05-26 19:03:08 [InstanceEdit:3150161] D'Eustachio, P, 2013-02-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9960864] D'Eustachio, Peter, 2025-07-17 [InstanceEdit:9987445] D'Eustachio, Peter, 2026-04-15 [InstanceEdit:9987448] D'Eustachio, Peter, 2026-04-15 [InstanceEdit:9987670] D'Eustachio, Peter, 2026-04-23
name	3,7,24THCA-CoA is translocated from the cytosol to the peroxisome 3,7,24THCA-CoA [ cytosol] => 3,7,24THCA-CoA [peroxisome]
output	[SimpleEntity:193732] 3,7,24THCA-CoA [peroxisomal matrix] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:29372] Pi [cytosol]
precedingEvent	[Reaction:193743] 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) [Homo sapiens] [BlackBoxEvent:193786] 3,7,24THCA is translocated from the mitochondrial matrix to the cytosol [Homo sapiens] [Reaction:193711] 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) [Homo sapiens] [BlackBoxEvent:193786] 3,7,24THCA is translocated from the mitochondrial matrix to the cytosol [Homo sapiens]
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2007-05-15
reviewed	[InstanceEdit:197117] D'Eustachio, P, 2007-04-30 14:43:26 [InstanceEdit:9987671] Hill, David P, 2026-04-23
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:361570] R-HSA-193753.3
structureModified	[InstanceEdit:9987445] D'Eustachio, Peter, 2026-04-15
summation	[Summation:193723] 3,7,24THCA-CoA is transported from the cytosol into the pero...
(hasEvent)	[Pathway:193775] Synthesis of bile acids and bile salts via 24-hydroxycholesterol [Homo sapiens]
(precedingEvent)	[Reaction:193736] Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9792298] Update Tracker - [Reaction:193753] 3,7,24THCA-CoA is translocated from the cytosol to the peroxisome - v22:[addLiteratureReference] [_UpdateTracker:9964613] Update Tracker - [BlackBoxEvent:193753] 3,7,24THCA-CoA is translocated from the cytosol to the peroxisome - v94:[modifyText, removeLiteratureReference]
[Change default viewing format]

No pathways have been reviewed or authored by 3,7,24THCA-CoA is translocated from the cytosol to the peroxisome (193753)