Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person Sterol 12alpha hydroxylase (CYP8B1) catalyses the 12-alpha-h...
| Class:Id | Summation:193738 |
|---|---|
| _displayName | Sterol 12alpha hydroxylase (CYP8B1) catalyses the 12-alpha-h... |
| _timestamp | 2024-04-15 21:38:04 |
| created | [InstanceEdit:193768] D'Eustachio, P, 2007-02-23 20:48:08 |
| literatureReference | [LiteratureReference:5602286] Purification and characterization of 7 alpha-hydroxy-4-cholesten-3-one 12 alpha-hydroxylase [LiteratureReference:192101] Structure and chromosomal assignment of the sterol 12alpha-hydroxylase gene (CYP8B1) in human and mouse: eukaryotic cytochrome P-450 gene devoid of introns |
| modified | [InstanceEdit:5602279] Jassal, Bijay, 2014-06-23 [InstanceEdit:8940214] D'Eustachio, Peter, 2016-09-23 [InstanceEdit:9907727] D'Eustachio, Peter, 2024-04-15 |
| text | Sterol 12alpha hydroxylase (CYP8B1) catalyses the 12-alpha-hydroxylation of 4-cholesten-7alpha,24(S)-diol-3-one (4CHOL7a,24(S)DONE) to 4-cholesten-7-alpha,12-alpha,24(S)-triol-3-one (4CHOL7a,12a,24(S)TONE). While the human gene has been cloned (Gafvels et al. 1999), its protein product has not been characterised, and the enzymatic properties of human CYP8B1 protein are inferred from those of its well-characterised rabbit homolog (Ishida et al. 1992). These papers support Reaction:192157 "CYP8B1 12-hydroxylates 4CHOL7aOLONE" but not this one, so this reaction has been set to _doRelease = false. |
| (summation) | [Reaction:193709] CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by Sterol 12alpha hydroxylase (CYP8B1) catalyses the 12-alpha-h... (193738)
