Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person IKKbeta is activated

Class:IdReaction:193703
_displayNameIKKbeta is activated
_doReleaseTRUE
_timestamp2010-02-24 10:01:55
authored[InstanceEdit:188342] Nasi, Sergio, Annibali, D, 2006-10-10
catalystActivity[CatalystActivity:193885] protein serine/threonine kinase activity of NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62:IKK-beta [plasma membrane]
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:193693] Jassal, B, 2007-02-23 15:02:35
edited[InstanceEdit:350668] Jassal, B, 2008-05-20 12:26:36
input[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[Complex:209533] NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62:IKK-beta [plasma membrane] [Homo sapiens]
literatureReference[LiteratureReference:193862] Activation of IkappaB kinase beta by protein kinase C isoforms
modified[InstanceEdit:193875] Jassal, B, 2007-03-01 15:14:39
[InstanceEdit:209557] Jassal, B, 2007-12-19 10:40:30
[InstanceEdit:266359] Gopinathrao, G, 2008-05-06 14:37:06
[InstanceEdit:350675] Jassal, B, 2008-05-20 13:02:11
[InstanceEdit:351794] Jassal, B, 2008-05-28 09:47:11
[InstanceEdit:528073] Jassal, B, 2010-02-24
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameIKKbeta is activated
output[Complex:209565] NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62:Phospho-IKK-beta [plasma membrane] [Homo sapiens]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
precedingEvent
releaseDate2008-06-30
reviewed[InstanceEdit:350667] Friedman, WJ, 2008-05-20 12:23:46
[InstanceEdit:351795] Chao, MV, 2008-05-28 09:46:01
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:361248] R-HSA-193703.2
summation[Summation:193939] Atypical PKC isoforms phosphorylate the beta subunit of the ...
(hasEvent)[Pathway:209560] NF-kB is activated and signals survival [Homo sapiens]
(precedingEvent)[Reaction:193705] IKKbeta phosphorylates IkB causing NF-kB to dissociate [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by IKKbeta is activated (193703)