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Details on Person p62 is recruited and forms a complex with TRAF6

Class:Id	Reaction:193694
_displayName	p62 is recruited and forms a complex with TRAF6
_doRelease	TRUE
_timestamp	2010-05-06 08:19:43
authored	[InstanceEdit:188342] Nasi, Sergio, Annibali, D, 2006-10-10
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:193693] Jassal, B, 2007-02-23 15:02:35
edited	[InstanceEdit:350668] Jassal, B, 2008-05-20 12:26:36
input	[Complex:209569] NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:193937] SQSTM1 [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:193869] The atypical PKC-interacting protein p62 channels NF-kappaB activation by the IL-1-TRAF6 pathway [LiteratureReference:193906] The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor
modified	[InstanceEdit:193875] Jassal, B, 2007-03-01 15:14:39 [InstanceEdit:209557] Jassal, B, 2007-12-19 10:40:30 [InstanceEdit:216362] Jassal, B, 2008-03-14 11:00:22 [InstanceEdit:266359] Gopinathrao, G, 2008-05-06 14:37:06 [InstanceEdit:350686] Jassal, B, 2008-05-20 13:27:31 [InstanceEdit:351794] Jassal, B, 2008-05-28 09:47:11 [InstanceEdit:681588] Jassal, B, 2010-05-06 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	p62 is recruited and forms a complex with TRAF6
output	[Complex:209577] NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:193665] MYD88 dissociates [Homo sapiens] [Reaction:193695] IRAK interacts with TRAF6 [Homo sapiens]
releaseDate	2008-06-30
reviewed	[InstanceEdit:350667] Friedman, WJ, 2008-05-20 12:23:46 [InstanceEdit:351795] Chao, MV, 2008-05-28 09:46:01
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:361487] R-HSA-193694.2
summation	[Summation:193858] NGF binding to p75NTR induces recruitment of the atypical PK...
(hasEvent)	[Pathway:209543] p75NTR recruits signalling complexes [Homo sapiens]
(precedingEvent)	[Reaction:193641] IKK-beta is recruited [Homo sapiens] [BlackBoxEvent:209566] TRAF6 is auto-ubiquitinated [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9791161] Update Tracker - [Reaction:193694] p62 is recruited and forms a complex with TRAF6 - v32:[modifyText]
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