Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person TRAF6 binds to p75NTR:NRIF

Class:IdReaction:193669
_displayNameTRAF6 binds to p75NTR:NRIF
_doReleaseTRUE
_timestamp2009-06-03 14:26:31
authored[InstanceEdit:188342] Nasi, Sergio, Annibali, D, 2006-10-10
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:193693] Jassal, B, 2007-02-23 15:02:35
edited[InstanceEdit:350668] Jassal, B, 2008-05-20 12:26:36
input[Complex:205100] NGF ligand:p75NTR:NRIF [plasma membrane] [Homo sapiens]
[Complex:421373] TRAF6 homotrimer [cytosol] [Homo sapiens]
literatureReference[LiteratureReference:204956] A functional interaction between the p75 neurotrophin receptor interacting factors, TRAF6 and NRIF
modified[InstanceEdit:194346] Jassal, B, 2007-03-13 16:41:41
[InstanceEdit:194750] Jassal, B, 2007-03-27 11:17:51
[InstanceEdit:204953] Jassal, B, 2007-12-06 11:10:12
[InstanceEdit:266359] Gopinathrao, G, 2008-05-06 14:37:06
[InstanceEdit:350354] Jassal, B, 2008-05-19 08:15:51
[InstanceEdit:350684] Jassal, B, 2008-05-20 13:25:17
[InstanceEdit:350849] Jassal, B, 2008-05-21 10:36:56
[InstanceEdit:351794] Jassal, B, 2008-05-28 09:47:11
[InstanceEdit:425219] Jassal, B, 2009-06-03
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameTRAF6 binds to p75NTR:NRIF
output[Complex:204977] NGF ligand:p75NTR:NRIF:TRAF6 [plasma membrane] [Homo sapiens]
precedingEvent
releaseDate2008-06-30
reviewed[InstanceEdit:350667] Friedman, WJ, 2008-05-20 12:23:46
[InstanceEdit:351795] Chao, MV, 2008-05-28 09:46:01
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:361786] R-HSA-193669.2
summation[Summation:194359] Upon neurotrophin stimulation, p75NTR interacts with the ubi...
(hasEvent)[Pathway:205043] NRIF signals cell death from the nucleus [Homo sapiens]
(precedingEvent)[Reaction:193666] Active JNK moves to the nucleus and phosphorylates different transcription factors [Homo sapiens]
[Reaction:204949] NRIF and TRAF6 may activate JNK [Homo sapiens]
[Reaction:205112] gamma-secretase cleaves p75NTR, releasing NRIF and TRAF6 [Homo sapiens]
[Reaction:9673322] p-T,Y-MAPK8 translocates from the cytosol to the nucleoplasm [Homo sapiens]
(updatedInstance)[_UpdateTracker:9791554] Update Tracker - [Reaction:193669] TRAF6 binds to p75NTR:NRIF - v29:[add_removeInput]
[Change default viewing format]
No pathways have been reviewed or authored by TRAF6 binds to p75NTR:NRIF (193669)