Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person Chenodeoxycholoyl CoA reacts with glycine or taurine to form...

Class:IdSummation:193501
_displayNameChenodeoxycholoyl CoA reacts with glycine or taurine to form...
_timestamp2007-02-19 17:37:11
created[InstanceEdit:193476] D'Eustachio, P, 2007-02-19 17:36:33
literatureReference[LiteratureReference:159413] Glycine and taurine conjugation of bile acids by a single enzyme. Molecular cloning and expression of human liver bile acid CoA:amino acid N-acyltransferase.
[LiteratureReference:193432] Participation of two members of the very long-chain acyl-CoA synthetase family in bile acid synthesis and recycling
[LiteratureReference:193480] Subcellular organization of bile acid amidation in human liver: a key issue in regulating the biosynthesis of bile salts
[LiteratureReference:192080] The enzymes, regulation, and genetics of bile acid synthesis
textChenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate, releasing CoASH. This reaction, which completes the de novo synthesis of bile salts from cholesterol in vivo, is catalyzed by BAAT (Bile acid CoA:amino acid N-acyltransferase - Falany et al. 1994) and occurs in the peroxisomal matrix (Solaas et al. 2000; Mihalik et al. 2002). In vivo, the relative amounts of glycochenodeoxycholate and taurochenodeoxycholate synthesized appear to be determined solely by the intracellular abundances of glycine and taurine (Russell 2003).
(summation)[Reaction:193491] Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by Chenodeoxycholoyl CoA reacts with glycine or taurine to form... (193501)
Follow Reactome