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Details on Person Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA

Class:Id	Reaction:193452
_displayName	Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA
_doRelease	TRUE
_timestamp	2008-06-20 09:43:28
authored	[InstanceEdit:191331] Jassal, Bijay, 2007-01-19
catalystActivity	[CatalystActivity:191973] racemase and epimerase activity of AMACR [peroxisomal matrix]
compartment	[Compartment:17951] peroxisomal matrix
created	[InstanceEdit:193476] D'Eustachio, P, 2007-02-19 17:36:33
edited	[InstanceEdit:193475] D'Eustachio, P, 2007-02-17 19:40:28
input	[SimpleEntity:193429] 25(R) DHCA-CoA [peroxisomal matrix]
literatureReference	[LiteratureReference:192112] Purification and characterization of an alpha-methylacyl-CoA racemase from human liver [LiteratureReference:192185] Mitochondrial and peroxisomal targeting of 2-methylacyl-CoA racemase in humans [LiteratureReference:193502] Mutations in the gene encoding peroxisomal alpha-methylacyl-CoA racemase cause adult-onset sensory motor neuropathy
modified	[InstanceEdit:195718] Gopinathrao, G, 2007-04-16 17:35:22 [InstanceEdit:197014] Gopinathrao, G, 2007-04-30 12:01:02 [InstanceEdit:197116] D'Eustachio, P, 2007-04-30 14:50:16 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA 25(R) DHCA-CoA => 25(S) DHCA-CoA
output	[SimpleEntity:193442] 25(S) DHCA-CoA [peroxisomal matrix]
precedingEvent	[Reaction:193482] 25(R) DHCA-CoA is translocated from the cytosol to the peroxisome [Homo sapiens] [Reaction:193424] DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) [Homo sapiens] [Reaction:193407] DHCA is conjugated with Coenzyme A (SLC27A5 BACS) [Homo sapiens]
releaseDate	2007-05-15
reviewed	[InstanceEdit:197117] D'Eustachio, P, 2007-04-30 14:43:26
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:361081] R-HSA-193452.2
summation	[Summation:193417] The isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA, catal...
(hasEvent)	[Pathway:193368] Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol [Homo sapiens]
(precedingEvent)	[Reaction:193369] 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA [Homo sapiens]
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No pathways have been reviewed or authored by Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA (193452)