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Details on Person THCA (25(R) 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan...

Class:IdSummation:193413
_displayNameTHCA (25(R) 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan...
_timestamp2010-04-05 19:40:45
created[InstanceEdit:193476] D'Eustachio, P, 2007-02-19 17:36:33
modified[InstanceEdit:194078] D'Eustachio, P, 2007-03-08 15:03:08
[InstanceEdit:564713] D'Eustachio, P, 2010-04-05
textTHCA (25(R) 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate), coenzyme A, and ATP react to form the CoA conjugate of 25(R) THCA, AMP, and pyrophosphate. This cytosolic reaction is catalyzed by SLC27A2 (VLCS). SLC27A5 (BACS) also catalyzes this reaction; the relative contributions of the two enzymes to de novo bile acid synthesis in vivo are not certain (Mihalik et al. 2002).
(summation)[Reaction:193401] THCA is conjugated with Coenzyme A (SLC27A2 VLCS) [Homo sapiens]
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No pathways have been reviewed or authored by THCA (25(R) 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan... (193413)