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Details on Person CHOL [endoplasmic reticulum membrane]

Class:Id	SimpleEntity:193384
_displayName	CHOL [endoplasmic reticulum membrane]
_timestamp	2013-12-13 14:07:06
compartment	[Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:193476] D'Eustachio, P, 2007-02-19 17:36:33
crossReference	[DatabaseIdentifier:29711] COMPOUND:C00187
modified	[InstanceEdit:5212701] Jassal, B, 2013-12-13 [InstanceEdit:9616752] Shorser, Solomon, 2018-08-13 [InstanceEdit:9619952] Wu, G, 2018-09-19
name	CHOL cholesterol
referenceEntity	[ReferenceMolecule:29710] cholesterol [ChEBI:16113]
stableIdentifier	[StableIdentifier:369639] R-ALL-193384.3
(hasComponent)	[Complex:1655741] SCAP:cholesterol [endoplasmic reticulum membrane] [Homo sapiens] [Complex:1655758] SCAP:cholesterol [endoplasmic reticulum membrane] [Cricetulus griseus]
(input)	[Reaction:192051] CYP7A1 7-hydroxylates CHOL [Homo sapiens] [Reaction:192061] CYP46A1 24-hydroxylates CHOL [Homo sapiens] [BlackBoxEvent:2317526] SREBP1A/1C/2 is retained in the endoplasmic reticulum by SCAP:cholesterol:INSIG [Cricetulus griseus] [Reaction:2317530] SREBP1A,1C,2 binds SCAP:cholesterol:INSIG and is retained in the endoplasmic reticulum [Homo sapiens] [Reaction:5250531] ARV1 transports CHOL from ER membrane to plasma membrane [Homo sapiens] [BlackBoxEvent:5250548] Arv1 transports CHOL from ER membrane to plasma membrane [Saccharomyces cerevisiae] [Reaction:8876696] SOAT1,2 transfer acyl group to CHOL forming CHEST [Homo sapiens]
(output)	[Reaction:196417] Reduction of desmosterol to cholesterol [Homo sapiens] [Reaction:6807055] DHCR7 reduces 7-dehydroCHOL to CHOL [Homo sapiens] [BlackBoxEvent:8876485] CHOL translocates from lysosome membrane to ER membrane [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9888822] Update Tracker - [SimpleEntity:193384] CHOL [endoplasmic reticulum membrane] - v48:[addName] [_UpdateTracker:9892037] Update Tracker - [SimpleEntity:193384] CHOL [endoplasmic reticulum membrane] - v52:[modifyName]
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No pathways have been reviewed or authored by CHOL [endoplasmic reticulum membrane] (193384)