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Details on Person Activities of recombinant human cytochrome P450c27 (CYP27) which produce intermediates of alternative bile acid biosynthetic pathways
| Class:Id | LiteratureReference:193375 |
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| _displayName | Activities of recombinant human cytochrome P450c27 (CYP27) which produce intermediates of alternative bile acid biosynthetic pathways |
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| _timestamp | 2007-02-19 17:36:56 |
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| author | [Person:192204] Pikuleva, IA
[Person:193539] Babiker, A
[Person:193061] Waterman, MR
[Person:192041] Bjorkhem, I |
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| created | [InstanceEdit:193476] D'Eustachio, P, 2007-02-19 17:36:33 |
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| journal | J Biol Chem |
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| pages | 18153-60 |
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| pubMedIdentifier | 9660774 |
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| title | Activities of recombinant human cytochrome P450c27 (CYP27) which produce intermediates of alternative bile acid biosynthetic pathways |
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| volume | 273 |
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| year | 1998 |
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| (literatureReference) | [Reaction:191999] CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol [Homo sapiens]
[Reaction:192042] 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al [Homo sapiens]
[Reaction:192054] 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) [Homo sapiens]
[Reaction:193393] 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol [Homo sapiens]
[Reaction:193460] 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) [Homo sapiens]
[Reaction:193497] 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al [Homo sapiens]
[Reaction:193713] 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) [Homo sapiens]
[Reaction:193719] 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al [Homo sapiens]
[Reaction:193737] 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) [Homo sapiens]
[Reaction:193780] 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al [Homo sapiens] |
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