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Details on Person In this two-step reaction catalyzed by 3beta-HSD associated ...

Class:IdSummation:193085
_displayNameIn this two-step reaction catalyzed by 3beta-HSD associated ...
_timestamp2011-08-23 16:21:25
created[InstanceEdit:193053] Jassal, B, 2007-02-13 10:16:33
modified[InstanceEdit:196399] D'Eustachio, P, 2007-04-21 16:30:10
[InstanceEdit:1502543] Jassal, B, 2011-08-23
textIn this two-step reaction catalyzed by 3beta-HSD associated with the endoplasmic reticulum membrane, the 3-hydroxyl group of DHA is oxidized to a keto group and the double bond in the steroid nucleus is then isomerized from the five to the 4 position. Corticotropin (Adrenocorticotropic hormone, ACTH) acts through the ACTH receptor called melanocortin receptor type 2 (MC2R) to stimulate steroidogenesis, increasing the production of androgens (McKenna et al, 1997).
(summation)[Reaction:193073] HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST [Homo sapiens]
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No pathways have been reviewed or authored by In this two-step reaction catalyzed by 3beta-HSD associated ... (193085)