Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase)

Class:IdReaction:192417
_displayNameDigestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase)
_doReleaseTRUE
_timestamp2025-11-05 17:02:40
authored[InstanceEdit:192484] D'Eustachio, P, 2007-02-02 21:43:49
catalystActivity[CatalystActivity:192461] sterol ester esterase activity of dimerized CEL:bile salt complex [extracellular region]
compartment[Compartment:984] extracellular region
created[InstanceEdit:192484] D'Eustachio, P, 2007-02-02 21:43:49
crossReference[DatabaseIdentifier:9966218] RHEA:10101
input[SimpleEntity:171076] CHEST [extracellular region]
[SimpleEntity:109276] H2O [extracellular region]
internalReviewed[InstanceEdit:9971318] D'Eustachio, Peter, 2025-11-05
literatureReference[LiteratureReference:192471] Studies on the substrate specificity of a carboxyl ester hydrolase from human pancreatic juice. II. Action on cholesterol esters and lipid-soluble vitamin esters.
modified[InstanceEdit:193359] Gopinathrao, G, 2007-02-16 20:25:31
[InstanceEdit:6793336] Jassal, Bijay, 2015-09-01
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9966227] Stephan, Ralf, 2025-09-13
[InstanceEdit:9971317] D'Eustachio, Peter, 2025-11-05
[InstanceEdit:9971321] D'Eustachio, Peter, 2025-11-05
nameDigestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase)
output[SimpleEntity:171149] CHOL [extracellular region]
[SimpleEntity:174602] LCFAs [extracellular region]
[SimpleEntity:351626] H+ [extracellular region]
previousReviewStatus[ReviewStatus:9821385] four stars
releaseDate2007-02-20
reviewed[InstanceEdit:9971320] D'Eustachio, Peter, 2025-11-05
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:361436] R-HSA-192417.4
structureModified[InstanceEdit:9966227] Stephan, Ralf, 2025-09-13
summation[Summation:192426] CEL (bile salt-dependent lipase) catalyzes the hydrolysis of...
(hasEvent)[Pathway:192456] Digestion of dietary lipid [Homo sapiens]
(precedingEvent)[Reaction:265443] NPC1L1-mediated cholesterol uptake [Homo sapiens]
(updatedInstance)[_UpdateTracker:9791922] Update Tracker - [Reaction:192417] Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) - v25:[modifyText]
[_UpdateTracker:9971915] Update Tracker - [Reaction:192417] Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) - v95:[removeOutput]
[Change default viewing format]
No pathways have been reviewed or authored by Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) (192417)