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Details on Person Characterization of human sterol 27-hydroxylase. A mitochondrial cytochrome P-450 that catalyzes multiple oxidation reaction in bile acid biosynthesis.

Class:IdLiteratureReference:192197
_displayNameCharacterization of human sterol 27-hydroxylase. A mitochondrial cytochrome P-450 that catalyzes multiple oxidation reaction in bile acid biosynthesis.
_timestamp2007-01-26 15:42:21
author[Person:192014] Cali, JJ
[Person:192138] Russell, David W
created[InstanceEdit:191989] Jassal, Bijay, 2007-01-26
journalJ Biol Chem
pages7774-8
pubMedIdentifier1708392
titleCharacterization of human sterol 27-hydroxylase. A mitochondrial cytochrome P-450 that catalyzes multiple oxidation reaction in bile acid biosynthesis.
volume266
year1991
(literatureReference)[Reaction:191999] CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol [Homo sapiens]
[Reaction:192042] 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al [Homo sapiens]
[Reaction:192054] 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) [Homo sapiens]
[Reaction:192123] CYP27A1 27-hydroxylates CHOL [Homo sapiens]
[Reaction:193393] 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol [Homo sapiens]
[Reaction:193460] 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) [Homo sapiens]
[Reaction:193497] 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al [Homo sapiens]
[Reaction:193713] 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) [Homo sapiens]
[Reaction:193719] 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al [Homo sapiens]
[Reaction:193737] 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) [Homo sapiens]
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