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Details on Person Characterization of human sterol 27-hydroxylase. A mitochondrial cytochrome P-450 that catalyzes multiple oxidation reaction in bile acid biosynthesis.
| Class:Id | LiteratureReference:192197 |
| _displayName | Characterization of human sterol 27-hydroxylase. A mitochondrial cytochrome P-450 that catalyzes multiple oxidation reaction in bile acid biosynthesis. |
| _timestamp | 2007-01-26 15:42:21 |
| author | [Person:192014] Cali, JJ [Person:192138] Russell, David W |
| created | [InstanceEdit:191989] Jassal, Bijay, 2007-01-26 |
| journal | J Biol Chem |
| pages | 7774-8 |
| pubMedIdentifier | 1708392 |
| title | Characterization of human sterol 27-hydroxylase. A mitochondrial cytochrome P-450 that catalyzes multiple oxidation reaction in bile acid biosynthesis. |
| volume | 266 |
| year | 1991 |
| (literatureReference) | [Reaction:191999] CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol [Homo sapiens] [Reaction:192042] 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al [Homo sapiens] [Reaction:192054] 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) [Homo sapiens] [Reaction:192123] CYP27A1 27-hydroxylates CHOL [Homo sapiens] [Reaction:193393] 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol [Homo sapiens] [Reaction:193460] 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) [Homo sapiens] [Reaction:193497] 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al [Homo sapiens] [Reaction:193713] 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) [Homo sapiens] [Reaction:193719] 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al [Homo sapiens] [Reaction:193737] 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) [Homo sapiens] |
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