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Details on Person Cholesterol (CHOL), NADPH + H+, and O2 react to form 27-hydr...
| Class:Id | Summation:192152 |
|---|---|
| _displayName | Cholesterol (CHOL), NADPH + H+, and O2 react to form 27-hydr... |
| _timestamp | 2026-04-29 20:05:01 |
| created | [InstanceEdit:191989] Jassal, Bijay, 2007-01-26 |
| literatureReference | [LiteratureReference:193802] Elimination of cholesterol as cholestenoic acid in human lung by sterol 27-hydroxylase: evidence that most of this steroid in the circulation is of pulmonary origin |
| modified | [InstanceEdit:193803] D'Eustachio, P, 2007-02-27 22:01:10 [InstanceEdit:5602279] Jassal, Bijay, 2014-06-23 [InstanceEdit:9987901] D'Eustachio, Peter, 2026-04-29 |
| text | Cholesterol (CHOL), NADPH + H+, and O2 react to form 27-hydroxycholesterol (27OH-CHOL), H2O, and NADP+, in the mitochondrial matrix, catalysed by CYP27A1. 27OH-CHOL is the most abundant oxysterol in human plasma. Its formation is thought to play a central role in the mobilization of CHOL from non-hepatic tissues (Cali et al. 1991). |
| (summation) | [Reaction:192123] CYP27A1 27-hydroxylates CHOL [Homo sapiens] |
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No pathways have been reviewed or authored by Cholesterol (CHOL), NADPH + H+, and O2 react to form 27-hydr... (192152)
