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Query author contributions in Reactome

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Details on Person Cholesterol 24-hydroxylase (CYP46A1), an enzyme associated w...

Class:IdSummation:191967
_displayNameCholesterol 24-hydroxylase (CYP46A1), an enzyme associated w...
_timestamp2014-06-23 14:49:13
created[InstanceEdit:191989] Jassal, Bijay, 2007-01-26
literatureReference[LiteratureReference:193584] Cholesterol, hydroxycholesterols, and bile acids
modified[InstanceEdit:193586] D'Eustachio, P, 2007-02-21 16:52:00
[InstanceEdit:5602279] Jassal, Bijay, 2014-06-23
textCholesterol 24-hydroxylase (CYP46A1), an enzyme associated with the ER membrane, catalyses the 24-hydroxylation of cholesterol (CHOL) to 24-hydroxycholesterol (24OH-CHOL). In the body, this enzyme is expressed predominantly in the brain and is thought to play a major role in cholesterol turnover there (Lund et al. 1999, Mast et al. 2003).
(summation)[Reaction:192061] CYP46A1 24-hydroxylates CHOL [Homo sapiens]
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