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Details on Person Loading and methylation of Sm proteins onto SMN Complexes

Class:IdReaction:191790
_displayNameLoading and methylation of Sm proteins onto SMN Complexes
_doReleaseTRUE
_timestamp2008-06-20 09:39:11
authored[InstanceEdit:192216] Gillespie, ME, 2007-01-29 20:29:54
catalystActivity[CatalystActivity:191843] protein-arginine N-methyltransferase activity of Methylosome [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:191793] Gillespie, ME, 2007-01-25 05:18:34
figure[Figure:191845] /figures/snRNPAssembly_Smload.jpg
goBiologicalProcess[GO_BiologicalProcess:81927] spliceosomal snRNP assembly
input[EntityWithAccessionedSequence:191798] SNRPB [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:191890] SNRPD1 [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:191810] SNRPD2 [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:191781] 2xMe-SNRPD3 [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:191782] SNRPE [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:191852] SNRPF [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:191827] SNRPG [cytosol] [Homo sapiens]
[Complex:191881] SMN complex [cytosol] [Homo sapiens]
[SimpleEntity:71284] AdoMet [cytosol]
literatureReference[LiteratureReference:191817] Gemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems
[LiteratureReference:191895] Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli.
[LiteratureReference:191842] Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins
[LiteratureReference:191828] Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component
[LiteratureReference:191764] Identification and characterization of Gemin7, a novel component of the survival of motor neuron complex
[LiteratureReference:191807] Specific sequences of the Sm and Sm-like (Lsm) proteins mediate their interaction with the spinal muscular atrophy disease gene product (SMN)
modified[InstanceEdit:192222] Gillespie, ME, 2007-01-29 20:30:07
[InstanceEdit:195718] Gopinathrao, G, 2007-04-16 17:35:22
[InstanceEdit:196902] Gopinathrao, G, 2007-04-25 14:00:12
[InstanceEdit:197013] Gopinathrao, G, 2007-04-30 09:21:41
[InstanceEdit:197144] Gillespie, ME, 2007-04-30 18:30:20
[InstanceEdit:197147] Gillespie, ME, 2007-04-30 18:33:13
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameLoading and methylation of Sm proteins onto SMN Complexes
output[Complex:191791] SMN:SM protein complex [cytosol] [Homo sapiens]
releaseDate2007-05-15
reviewed[InstanceEdit:197146] Luhrmann, R, 2007-04-30 18:31:22
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:358349] R-HSA-191790.2
summation[Summation:191766] The survival of motor neurons (SMN) complex binds to Sm prot...
(hasEvent)[Pathway:191859] snRNP Assembly [Homo sapiens]
(precedingEvent)[Reaction:191786] snRNP complex assembly [Homo sapiens]
(updatedInstance)[_UpdateTracker:9782177] Update Tracker - [Reaction:191790] Loading and methylation of Sm proteins onto SMN Complexes - v59:[modifyText]
[_UpdateTracker:9789657] Update Tracker - [Reaction:191790] Loading and methylation of Sm proteins onto SMN Complexes - v37:[modifyText]
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