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Details on Person The prenyltransferase enzyme family is involved in the biosy...

Class:IdSummation:191364
_displayNameThe prenyltransferase enzyme family is involved in the biosy...
_timestamp2025-10-23 21:30:46
created[InstanceEdit:191331] Jassal, Bijay, 2007-01-19
modified[InstanceEdit:191585] D'Eustachio, P, 2007-01-20 20:43:27
[InstanceEdit:981563] Jassal, B, 2010-10-25
[InstanceEdit:9717837] Jassal, Bijay, 2021-03-15
[InstanceEdit:9969889] D'Eustachio, Peter, 2025-10-23
textThe prenyltransferase enzyme family is involved in the biosynthesis of isoprenoids. Two members of this family are known to catalyse the sequential condensation of isopentenyl pyrophosphate (IPPP) to dimethylallyl pyrophosphate (DMAPP): farnesyl pyrophosphate synthase dimer (FPPS dimer) and geranylgeranyl pyrophosphate synthetase hexamer (GGPPS hexamer) (Kavanaugh et al, 2006). Both enzymes utlise Mg2+ as cofactor (Chang et al. 2021).
(summation)[Reaction:191322] FDPS dimer transfers IPPP to DMAPP [Homo sapiens]
[Reaction:9717834] GGPS1 hexamer transfers IPPP to DMAPP [Homo sapiens]
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