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Details on Person FDPS dimer transfers IPPP to DMAPP

Class:IdReaction:191322
_displayNameFDPS dimer transfers IPPP to DMAPP
_doReleaseTRUE
_timestamp2025-06-06 20:51:46
authored[InstanceEdit:191754] Jassal, B, 2007-01-24 15:15:12
catalystActivity[CatalystActivity:981571] dimethylallyltranstransferase activity of holo-FDPS dimer [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:191331] Jassal, Bijay, 2007-01-19
crossReference[DatabaseIdentifier:9945091] RHEA:22409
edited[InstanceEdit:191754] Jassal, B, 2007-01-24 15:15:12
input[SimpleEntity:191324] DMAPP [cytosol]
[SimpleEntity:191362] IPPP [cytosol]
literatureReference[LiteratureReference:191398] Human geranylgeranyl diphosphate synthase. cDNA cloning and expression.
[LiteratureReference:191275] Human geranylgeranyl diphosphate synthase: isolation of the cDNA, chromosomal mapping and tissue expression
[LiteratureReference:981558] The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs
[LiteratureReference:9717838] Structure, catalysis, and inhibition mechanism of prenyltransferase
modified[InstanceEdit:191592] Jassal, B, 2007-01-22 10:51:54
[InstanceEdit:191758] Jassal, B, 2007-01-24 15:18:37
[InstanceEdit:192362] D'Eustachio, P, 2007-01-31 15:17:45
[InstanceEdit:197014] Gopinathrao, G, 2007-04-30 12:01:02
[InstanceEdit:981563] Jassal, B, 2010-10-25
[InstanceEdit:9717837] Jassal, Bijay, 2021-03-15
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9945102] D'Eustachio, Peter, 2025-04-10
[InstanceEdit:9954123] D'Eustachio, Peter, 2025-06-06
nameFDPS dimer transfers IPPP to DMAPP
isopentenyl diphosphate + dimethylallyl diphosphate => (2E)-geranyl diphosphate + diphosphate
Addition of isopentenyl pyrophosphate to DMAPP
output[SimpleEntity:191409] GPP [cytosol]
[SimpleEntity:111294] PPi [cytosol]
precedingEvent
releaseDate2007-02-20
reviewed[InstanceEdit:191591] D'Eustachio, P, 2007-01-22 01:32:07
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:358906] R-HSA-191322.5
summation[Summation:191364] The prenyltransferase enzyme family is involved in the biosy...
(hasEvent)[Pathway:9969896] Lanosterol biosynthesis [Homo sapiens]
(precedingEvent)[Reaction:191303] FDPS dimer transfers IPPP to GPP [Homo sapiens]
[Reaction:9717830] GGPS1 hexamer transfers IPPP to GPP [Homo sapiens]
(updatedInstance)[_UpdateTracker:9776098] Update Tracker - [Reaction:191322] FDPS dimer transfers IPPP to DMAPP - v77:[addLiteratureReference, modifyText]
[_UpdateTracker:9790176] Update Tracker - [Reaction:191322] FDPS dimer transfers IPPP to DMAPP - v35:[addLiteratureReference, add_removeCatalystActivity, modifyText]
[_UpdateTracker:9971861] Update Tracker - [Reaction:191322] FDPS dimer transfers IPPP to DMAPP - v95:[modifyText]
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No pathways have been reviewed or authored by FDPS dimer transfers IPPP to DMAPP (191322)
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