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Details on Person MIR206 microRNA binds 3'UTR of NOTCH3 mRNA

Class:Id	Reaction:1912366
_displayName	MIR206 microRNA binds 3'UTR of NOTCH3 mRNA
_doRelease	TRUE
_timestamp	2012-03-01 11:23:58
authored	[InstanceEdit:2121208] Egan, SE, Orlic-Milacic, M, 2011-11-14
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1912365] Orlic-Milacic, M, 2011-11-01
edited	[InstanceEdit:2106576] Orlic-Milacic, M, 2012-02-10 [InstanceEdit:2121209] May, B, 2012-02-09 [InstanceEdit:2098673] D'Eustachio, P, 2012-02-06 [InstanceEdit:1609686] Jupe, S, 2011-09-27 [InstanceEdit:2121211] Gillespie, ME, 2012-02-09
input	[EntityWithAccessionedSequence:1911478] NOTCH3 mRNA [cytosol] [Homo sapiens] [DefinedSet:1614243] miR-206 RISC [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:1890323] MicroRNA-206 targets notch3, activates apoptosis, and inhibits tumor cell migration and focus formation
modified	[InstanceEdit:1985681] Orlic-Milacic, M, 2011-11-11 [InstanceEdit:2023189] Orlic-Milacic, M, 2011-12-06 [InstanceEdit:2029534] Orlic-Milacic, M, 2012-01-04 [InstanceEdit:2032326] Orlic-Milacic, M, 2012-01-06 [InstanceEdit:2121213] Orlic-Milacic, M, 2012-02-13 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	MIR206 microRNA binds 3'UTR of NOTCH3 mRNA
output	[Complex:1911498] NOTCH3 mRNA:miR-206 RISC [cytosol] [Homo sapiens]
precedingEvent	[BlackBoxEvent:1912415] NOTCH3 gene transcription [Homo sapiens] [Reaction:9013631] NICD3 binds RBPJ and MAML in the nucleus [Homo sapiens] [Reaction:9017835] NOTCH1 coactivator complex binds NOTCH3 gene [Homo sapiens] [Reaction:9021364] ELF3 binds NOTCH3 gene promoter [Homo sapiens]
releaseDate	2012-03-13
reviewed	[InstanceEdit:2121207] Haw, R, 2012-02-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2158166] R-HSA-1912366.2
summation	[Summation:1852628] Translation of NOTCH3 mRNA is inhibited by microRNA miR-206 ...
(hasEvent)	[Pathway:1912408] Pre-NOTCH Transcription and Translation [Homo sapiens]
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No pathways have been reviewed or authored by MIR206 microRNA binds 3'UTR of NOTCH3 mRNA (1912366)