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Details on Person FGFR4 binds to FGF

Class:IdReaction:190265
_displayNameFGFR4 binds to FGF
_doReleaseTRUE
_timestamp2011-09-07 19:05:49
authored[InstanceEdit:190908] de Bono, B, 2007-01-10 10:27:18
compartment[Compartment:984] extracellular region
[Compartment:876] plasma membrane
created[InstanceEdit:190264] de Bono, B, 2006-12-18 16:08:15
edited[InstanceEdit:193360] de Bono, B, D'Eustachio, P, 2007-02-10 20:21:22
input[DefinedSet:189959] FGFR4-binding FGFs [extracellular region] [Homo sapiens]
[DefinedSet:189959] FGFR4-binding FGFs [extracellular region] [Homo sapiens]
[SimpleEntity:190915] HS [extracellular region]
[EntityWithAccessionedSequence:189921] FGFR4 [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:189921] FGFR4 [plasma membrane] [Homo sapiens]
literatureReference[LiteratureReference:190251] Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family.
[LiteratureReference:191519] Structural basis for fibroblast growth factor receptor activation
modified[InstanceEdit:190908] de Bono, B, 2007-01-10 10:27:18
[InstanceEdit:191579] de Bono, B, 2007-01-20 18:45:32
[InstanceEdit:192405] D'Eustachio, P, 2007-02-02 20:38:51
[InstanceEdit:192578] Gopinathrao, G, 2007-02-06 21:04:41
[InstanceEdit:192611] D'Eustachio, P, 2007-02-06 23:16:07
[InstanceEdit:193359] Gopinathrao, G, 2007-02-16 20:25:31
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:1235034] May, B, 2011-03-20
[InstanceEdit:1268178] Rothfels, K, 2011-05-09
[InstanceEdit:1308026] Rothfels, K, 2011-05-30
[InstanceEdit:1583057] Rothfels, K, 2011-09-07
[InstanceEdit:9606200] Wu, G, 2018-04-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameFGFR4 binds to FGF
output[Complex:190223] FGFR4 homodimer bound to FGF [plasma membrane] [Homo sapiens]
precedingEvent
regulatedBy[Requirement:190318] Requirement by 'HS [extracellular region]'
releaseDate2007-02-20
reviewed[InstanceEdit:192607] Mohammadi, M, 2007-02-06 21:44:35
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:1493881] Rothfels, K, 2011-08-16
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359177] R-HSA-190265.3
summation[Summation:191578] In this reaction, FGF receptor in the plasma membrane binds ...
(hasEvent)[Pathway:190322] FGFR4 ligand binding and activation [Homo sapiens]
(normalReaction)[Reaction:2012086] Constitutive dimerization of FGFR4 Y367C mutant [Homo sapiens]
[Reaction:2038946] Dimerization of FGFR4 mutants with enhanced kinase activity [Homo sapiens]
(precedingEvent)[Reaction:190326] Autocatalytic phosphorylation of FGFR4 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9788922] Update Tracker - [Reaction:190265] FGFR4 binds to FGF - v39:[add_removeRegulator]
[_UpdateTracker:9789747] Update Tracker - [Reaction:190265] FGFR4 binds to FGF - v37:[addLiteratureReference, add_removeInput, removeRegulator]
[_UpdateTracker:9842240] Update Tracker - [Reaction:190265] FGFR4 binds to FGF - v86:[modifyText]
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