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Details on Person FGFR1b homodimer [plasma membrane]

Class:IdComplex:190228
_displayNameFGFR1b homodimer [plasma membrane]
_timestamp2014-12-05 15:22:48
compartment[Compartment:876] plasma membrane
created[InstanceEdit:190229] de Bono, B, 2006-12-18 13:54:50
disease[Disease:1493885] bladder carcinoma
[Disease:1500576] breast cancer
[Disease:1248679] head and neck squamous cell carcinoma
[Disease:1981182] lung squamous cell carcinoma
[Disease:1500575] ovarian cancer
[Disease:1614291] rhabdomyosarcoma
hasComponent
modified[InstanceEdit:190308] de Bono, B, 2007-01-02 10:06:19
[InstanceEdit:5655225] Rothfels, Karen, 2014-12-05
nameFGFR1b homodimer
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:368319] R-HSA-190228.1
(diseaseEntity)[EntityFunctionalStatus:5654531] gain_of_function of FGFR1b homodimer [plasma membrane]
(hasComponent)[Complex:190226] FGFR1b homodimer bound to FGF [plasma membrane] [Homo sapiens]
(hasMember)[DefinedSet:1982053] Overexpressed FGFR1 homodimers [plasma membrane] [Homo sapiens]
(input)[Reaction:1982066] Ligand-independent phosphorylation of overexpressed FGFR1 [Homo sapiens]
(output)[Reaction:1982065] Ligand-independent dimerization of overexpressed FGFR1b [Homo sapiens]
(physicalEntity)[CatalystActivity:1982067] protein tyrosine kinase activity of FGFR1b homodimer [plasma membrane]
(updatedInstance)[_UpdateTracker:9891619] Update Tracker - [Complex:190228] FGFR1b homodimer [plasma membrane] - v52:[addDisease]
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No pathways have been reviewed or authored by FGFR1b homodimer [plasma membrane] (190228)
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