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Details on Person FGFR4 homodimer bound to FGF [plasma membrane]

Class:Id	Complex:190223
_displayName	FGFR4 homodimer bound to FGF [plasma membrane]
_timestamp	2012-04-27 18:27:57
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:190229] de Bono, B, 2006-12-18 13:54:50
hasComponent	[DefinedSet:189959] FGFR4-binding FGFs [extracellular region] [Homo sapiens] [DefinedSet:189959] FGFR4-binding FGFs [extracellular region] [Homo sapiens] [Complex:190224] FGFR4 homodimer [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:189921] FGFR4 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:189921] FGFR4 [plasma membrane] [Homo sapiens] [SimpleEntity:190915] HS [extracellular region]
modified	[InstanceEdit:190908] de Bono, B, 2007-01-10 10:27:18 [InstanceEdit:1315508] Rothfels, K, 2011-05-31 [InstanceEdit:2213009] Matthews, L, 2012-04-27
name	FGFR4 homodimer bound to FGF
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:369837] R-HSA-190223.1
(input)	[Reaction:190326] Autocatalytic phosphorylation of FGFR4 [Homo sapiens]
(normalEntity)	[EntityFunctionalStatus:5654466] gain_of_function of FGFR4 Y367C mutant dimer [plasma membrane] [EntityFunctionalStatus:5654468] gain_of_function of FGFR4 enhanced kinase mutant dimers [plasma membrane]
(output)	[Reaction:190265] FGFR4 binds to FGF [Homo sapiens]
(physicalEntity)	[CatalystActivity:190331] protein tyrosine kinase activity of FGFR4 homodimer bound to FGF [plasma membrane]
(updatedInstance)	[_UpdateTracker:9870151] Update Tracker - [Complex:190223] FGFR4 homodimer bound to FGF [plasma membrane] - v37:[addCompartment, updateContainedComponent] [_UpdateTracker:9872656] Update Tracker - [Complex:190223] FGFR4 homodimer bound to FGF [plasma membrane] - v41:[removeCompartment] [_UpdateTracker:9893531] Update Tracker - [Complex:190223] FGFR4 homodimer bound to FGF [plasma membrane] - v56:[updateContainedComponent]
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No pathways have been reviewed or authored by FGFR4 homodimer bound to FGF [plasma membrane] (190223)