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Details on Person FGF23 bound to Klotho and FGFR1c [plasma membrane]

Class:Id	Complex:190218
_displayName	FGF23 bound to Klotho and FGFR1c [plasma membrane]
_timestamp	2012-04-27 18:27:41
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:190220] de Bono, B, 2006-12-18 13:19:54
hasComponent	[Complex:190208] Klotho bound to FGF23 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:189891] FGF23(25-251) [extracellular region] [Homo sapiens] [Complex:190309] Klotho homodimer [plasma membrane] [Homo sapiens] [DefinedSet:190207] Klotho [extracellular region] [Homo sapiens] [DefinedSet:190207] Klotho [extracellular region] [Homo sapiens] [Complex:190208] Klotho bound to FGF23 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:189891] FGF23(25-251) [extracellular region] [Homo sapiens] [Complex:190309] Klotho homodimer [plasma membrane] [Homo sapiens] [DefinedSet:190207] Klotho [extracellular region] [Homo sapiens] [DefinedSet:190207] Klotho [extracellular region] [Homo sapiens] [SimpleEntity:190915] HS [extracellular region] [Complex:190222] FGFR1c homodimer [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:189897] FGFR1c [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:189897] FGFR1c [plasma membrane] [Homo sapiens]
modified	[InstanceEdit:190908] de Bono, B, 2007-01-10 10:27:18 [InstanceEdit:192405] D'Eustachio, P, 2007-02-02 20:38:51 [InstanceEdit:1315494] Rothfels, K, 2011-05-31 [InstanceEdit:2213009] Matthews, L, 2012-04-27
name	FGF23 bound to Klotho and FGFR1c
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:362127] R-HSA-190218.1
(input)	[Reaction:191062] Autocatalytic phosphorylation of Klotho-bound FGFR1c [Homo sapiens]
(output)	[Reaction:190268] FGFR1c binds to Klotho-bound FGF23 [Homo sapiens]
(physicalEntity)	[CatalystActivity:192397] protein tyrosine kinase activity of FGF23 bound to Klotho and FGFR1c [plasma membrane]
(updatedInstance)	[_UpdateTracker:9870116] Update Tracker - [Complex:190218] FGF23 bound to Klotho and FGFR1c [plasma membrane] - v37:[addCompartment, updateContainedComponent] [_UpdateTracker:9872556] Update Tracker - [Complex:190218] FGF23 bound to Klotho and FGFR1c [plasma membrane] - v41:[removeCompartment, updateContainedComponent]
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No pathways have been reviewed or authored by FGF23 bound to Klotho and FGFR1c [plasma membrane] (190218)