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Details on Person FGF10 activates Pdx1 expression in the developing early pancreatic bud

Class:Id	BlackBoxEvent:190088
_displayName	FGF10 activates Pdx1 expression in the developing early pancreatic bud
_doRelease	TRUE
_timestamp	2012-11-25 19:19:42
authored	[InstanceEdit:351500] Ferrer, J, Tello-Ruiz, MK, 2008-05-23
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:190102] Tello-Ruiz, MK, 2006-12-18 05:46:40
edited	[InstanceEdit:190295] Tello-Ruiz, MK, 2006-12-19 19:02:30
literatureReference	[LiteratureReference:190094] An endothelial-mesenchymal relay pathway regulates early phases of pancreas development [LiteratureReference:190085] Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis
modified	[InstanceEdit:190279] Tello-Ruiz, MK, 2006-12-18 20:27:37 [InstanceEdit:190295] Tello-Ruiz, MK, 2006-12-19 19:02:30 [InstanceEdit:194433] Schmidt, EE, 2007-03-13 12:36:50 [InstanceEdit:204749] D'Eustachio, P, 2007-11-29 23:00:25 [InstanceEdit:264465] D'Eustachio, P, 2008-03-31 20:05:19 [InstanceEdit:349684] D'Eustachio, P, 2008-05-12 21:51:33 [InstanceEdit:350214] D'Eustachio, P, 2008-05-14 17:51:53 [InstanceEdit:351498] D'Eustachio, P, 2008-05-23 22:55:12 [InstanceEdit:827347] D'Eustachio, P, 2010-05-26 [InstanceEdit:2671770] D'Eustachio, P, 2012-11-25 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	FGF10 activates Pdx1 expression in the developing early pancreatic bud
output	[EntityWithAccessionedSequence:216457] Pdx-1 [nucleoplasm] [Mus musculus]
regulatedBy	[PositiveRegulation:190293] Positive regulation by 'fgf10 [extracellular region]'
releaseDate	2008-06-30
reviewed	[InstanceEdit:349683] Jensen, J, 2008-05-12 21:46:53
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:361430] R-MMU-190088.3
summation	[Summation:190089] Double Fgf10/Hnf6 KO studies have shown that these two prote...
(inferredFrom)	[BlackBoxEvent:210769] HNF6- and FGF10-dependent synthesis of PDX1 protein [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9790522] Update Tracker - [BlackBoxEvent:190088] FGF10 activates Pdx1 expression in the developing early pancreatic bud - v33:[addOutput]
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No pathways have been reviewed or authored by FGF10 activates Pdx1 expression in the developing early pancreatic bud (190088)