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Details on Person Mitochondrial dALA translocates to cytosol

Class:Id	BlackBoxEvent:189456
_displayName	Mitochondrial dALA translocates to cytosol
_doRelease	TRUE
_timestamp	2025-07-21 15:22:58
authored	[InstanceEdit:191749] Jassal, B, D'Eustachio, P, 2007-01-24 10:19:49
compartment	[Compartment:17906] mitochondrial outer membrane
created	[InstanceEdit:189470] Jassal, B, 2006-11-20 11:41:56
edited	[InstanceEdit:191749] Jassal, B, D'Eustachio, P, 2007-01-24 10:19:49
goBiologicalProcess	[GO_BiologicalProcess:9910496] export from the mitochondrion
input	[SimpleEntity:189466] dALA [mitochondrial matrix]
literatureReference	[LiteratureReference:8984910] ATP-binding cassette B10 regulates early steps of heme synthesis [LiteratureReference:8984903] ATP Binding and Hydrolysis Properties of ABCB10 and Their Regulation by Glutathione
modified	[InstanceEdit:189973] Jassal, B, 2006-12-13 09:03:56 [InstanceEdit:190162] Jassal, B, 2006-12-18 09:12:35 [InstanceEdit:191748] Jassal, B, 2007-01-24 10:21:13 [InstanceEdit:191898] D'Eustachio, P, 2007-01-25 14:05:55 [InstanceEdit:193359] Gopinathrao, G, 2007-02-16 20:25:31 [InstanceEdit:421638] D'Eustachio, P, 2009-05-19 13:26:30 [InstanceEdit:2995335] Jassal, B, 2013-01-22 [InstanceEdit:8984961] Duenas, Corina, 2017-04-11 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9853619] D'Eustachio, Peter, 2023-11-17 [InstanceEdit:9854167] D'Eustachio, Peter, 2023-11-22 [InstanceEdit:9961202] D'Eustachio, Peter, 2025-07-21
name	Mitochondrial dALA translocates to cytosol 5-aminolevulinate(in) = 5-aminolevulinate(out) ALA is transported from the mitochondrial matrix to the cytosol
output	[SimpleEntity:189489] dALA [cytosol]
precedingEvent	[Reaction:189442] ALAS condenses SUCC-CoA and Gly to form dALA [Homo sapiens]
releaseDate	2007-02-20
reviewed	[InstanceEdit:191750] Sassa, S, 2007-01-24 10:18:36
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:421639] D'Eustachio, P, 2009-05-19 13:25:07 [InstanceEdit:9854168] D'Eustachio, Peter, 2023-11-22
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:358243] R-HSA-189456.5
summation	[Summation:189462] 5-aminolevulinate (dALA) is transported from the mitochondri...
(hasEvent)	[Pathway:189451] Heme biosynthesis [Homo sapiens]
(precedingEvent)	[Reaction:189439] ALAD condenses 2 dALAs to form PBG [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9780931] Update Tracker - [Reaction:189456] Mitochondrial dALA translocates to cytosol - v61:[addLiteratureReference, modifyText] [_UpdateTracker:9864235] Update Tracker - [Reaction:189456] Mitochondrial dALA translocates to cytosol - v88:[modifyText]
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