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Details on Person PPO oxidises PPGEN9 to PRIN9

Class:IdReaction:189423
_displayNamePPO oxidises PPGEN9 to PRIN9
_doReleaseTRUE
_timestamp2023-11-22 20:32:12
authored[InstanceEdit:191749] Jassal, B, D'Eustachio, P, 2007-01-24 10:19:49
catalystActivity[CatalystActivity:189420] oxygen-dependent protoporphyrinogen oxidase activity of 2xPPOX:FAD [mitochondrial intermembrane space]
catalystActivityReference[CatalystActivityReference:9853739] oxygen-dependent protoporphyrinogen oxidase activity of 2xPPOX:FAD [mitochondrial intermembrane space] Quantitative structural insight into human variegate porphyria disease
compartment[Compartment:17927] mitochondrial intermembrane space
created[InstanceEdit:189470] Jassal, B, 2006-11-20 11:41:56
edited[InstanceEdit:191749] Jassal, B, D'Eustachio, P, 2007-01-24 10:19:49
input[SimpleEntity:189478] PPGEN9 [mitochondrial intermembrane space]
[SimpleEntity:189461] O2 [mitochondrial intermembrane space]
[SimpleEntity:189461] O2 [mitochondrial intermembrane space]
[SimpleEntity:189461] O2 [mitochondrial intermembrane space]
literatureReference[LiteratureReference:190007] Human protoporphyrinogen oxidase: expression, purification, and characterization of the cloned enzyme
[LiteratureReference:9853725] Quantitative structural insight into human variegate porphyria disease
modified[InstanceEdit:190001] Jassal, B, 2006-12-13 11:53:35
[InstanceEdit:190162] Jassal, B, 2006-12-18 09:12:35
[InstanceEdit:191748] Jassal, B, 2007-01-24 10:21:13
[InstanceEdit:191898] D'Eustachio, P, 2007-01-25 14:05:55
[InstanceEdit:193359] Gopinathrao, G, 2007-02-16 20:25:31
[InstanceEdit:421638] D'Eustachio, P, 2009-05-19 13:26:30
[InstanceEdit:975967] Jassal, Bijay, 2010-10-11
[InstanceEdit:2995335] Jassal, B, 2013-01-22
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9853729] D'Eustachio, Peter, 2023-11-20
[InstanceEdit:9854167] D'Eustachio, Peter, 2023-11-22
namePPO oxidises PPGEN9 to PRIN9
3 O2 + protoporphyrinogen IX => 3 H2O2 + protoporphyrin IX
Oxidation of protoporphyrinogen IX to protoporphyrin IX
output[SimpleEntity:189463] PRIN9 [mitochondrial intermembrane space]
[SimpleEntity:189481] H2O2 [mitochondrial intermembrane space]
[SimpleEntity:189481] H2O2 [mitochondrial intermembrane space]
[SimpleEntity:189481] H2O2 [mitochondrial intermembrane space]
precedingEvent
releaseDate2007-02-20
reviewed[InstanceEdit:191750] Sassa, S, 2007-01-24 10:18:36
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:421639] D'Eustachio, P, 2009-05-19 13:25:07
[InstanceEdit:9854168] D'Eustachio, Peter, 2023-11-22
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:360061] R-HSA-189423.3
summation[Summation:190003] Six electrons are oxidized in protophorphyrinogen IX (PPGEN9...
(hasEvent)[Pathway:189451] Heme biosynthesis [Homo sapiens]
(inferredFrom)[Reaction:421452] 2 protoporphyrinogen IX + 3 O2 => 2 protoporphyrin IX + 6 H2O [Gallus gallus]
(precedingEvent)[BlackBoxEvent:189457] Mitochondrial intermembrane PRIN9 translocates to mitochondrial matrix [Homo sapiens]
(updatedInstance)[_UpdateTracker:9787555] Update Tracker - [Reaction:189423] PPO oxidises PPGEN9 to PRIN9 - v44:[modifyText]
[_UpdateTracker:9790151] Update Tracker - [Reaction:189423] PPO oxidises PPGEN9 to PRIN9 - v35:[add_removeOutput]
[_UpdateTracker:9864091] Update Tracker - [Reaction:189423] PPO oxidises PPGEN9 to PRIN9 - v88:[addLiteratureReference, modifyText]
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