Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
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Details on Person Most of the heme degraded in humans comes from hemoglobin. A...
| Class:Id | Summation:189405 |
|---|---|
| _displayName | Most of the heme degraded in humans comes from hemoglobin. A... |
| _timestamp | 2006-11-20 14:47:19 |
| created | [InstanceEdit:189470] Jassal, B, 2006-11-20 11:41:56 |
| modified | [InstanceEdit:189493] Jassal, B, 2006-11-20 14:47:17 |
| text | Most of the heme degraded in humans comes from hemoglobin. Approximately 6-8 grams of hemoglobin is degraded daily which is equivalent to approximately 300 milligrams of heme per day. Heme is not recycled so it must be degraded and excreted. The iron, however, is conserved. There are two steps to heme degradation; 1. cleavage of the heme ring by a microsomal heme oxygenase producing biliverdin 2. biliverdin is reduced to bilirubin. Bilirubin can then be conjugated with glucuronic acid and excreted. |
| (summation) | [Pathway:189483] Heme degradation [Homo sapiens] |
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No pathways have been reviewed or authored by Most of the heme degraded in humans comes from hemoglobin. A... (189405)
