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Details on Person trehalose + H2O => 2 D-glucose

Class:IdReaction:188985
_displayNametrehalose + H2O => 2 D-glucose
_doReleaseTRUE
_timestamp2025-09-13 08:11:43
authored[InstanceEdit:189111] D'Eustachio, P, 2006-11-03 14:36:07
catalystActivity[CatalystActivity:189044] alpha,alpha-trehalase activity of N-seryl-glycosylphosphatidylinositolethanolamine-TREH [plasma membrane]
compartment[Compartment:984] extracellular region
[Compartment:876] plasma membrane
created[InstanceEdit:189008] D'Eustachio, P, 2006-11-03 14:39:28
crossReference[DatabaseIdentifier:9966228] RHEA:32676
inferredFrom
input[SimpleEntity:189078] alpha,alpha-trehalose [extracellular region]
[SimpleEntity:109276] H2O [extracellular region]
literatureReference[LiteratureReference:5659964] Trehalose malabsorption causing intolerance to mushrooms. Report of a probable case
[LiteratureReference:189105] Purification and characterization of kidney and intestinal brush-border membrane trehalases from the rabbit
[LiteratureReference:5659958] Trehalase deficiency in Greenland
[LiteratureReference:189063] Molecular cloning, sequencing and expression of cDNA encoding human trehalase
[LiteratureReference:5659959] Trehalase deficiency in a family
[LiteratureReference:189109] Rabbit small intestinal trehalase. Purification, cDNA cloning, expression, and verification of glycosylphosphatidylinositol anchoring.
modified[InstanceEdit:191105] D'Eustachio, P, 2007-01-18 18:40:09
[InstanceEdit:193359] Gopinathrao, G, 2007-02-16 20:25:31
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:5659954] D'Eustachio, Peter, 2014-12-29
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9966227] Stephan, Ralf, 2025-09-13
nametrehalose + H2O => 2 D-glucose
Digestion of trehalose to yield glucose
output[SimpleEntity:70115] Glc [extracellular region]
[SimpleEntity:70115] Glc [extracellular region]
releaseDate2007-02-20
reviewed[InstanceEdit:191109] Nichols, BL, 2007-01-15 21:51:24
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359138] R-HSA-188985.3
summation[Summation:189064] Extracellular trehalose, a disaccharide, is cleaved by treha...
(hasEvent)[Pathway:189085] Digestion of dietary carbohydrate [Homo sapiens]
(precedingEvent)[Reaction:8932955] SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol [Homo sapiens]
(updatedInstance)[_UpdateTracker:9784870] Update Tracker - [Reaction:188985] trehalose + H2O => 2 D-glucose - v52:[addLiteratureReference, modifyText]
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No pathways have been reviewed or authored by trehalose + H2O => 2 D-glucose (188985)
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